While this macro-mineral is easily obtained from many foods, magnesium deficiencies are extremely common for many Americans. Alcohol consumption, the presence of fluoride, and the consumption of certain foods either increase our need for magnesium or decrease its absorption. Magnesium is not only one of the key nutrients required in both calcium utilization and protein synthesis, but it also plays a tremendous role in virtually every enzymatic reaction in our body. LifeSource Vitamins Magnesium Citrate softgels are fast-acting, safe, and ideal for anyone who has their sights set on attaining optimal levels of this vital nutrient.*

Blood Pressure: The FDA Announces Qualified Health Claim for Magnesium and Reduced Risk of High Blood Pressure: Click Here to see FDA – US Food & Drug Administration website, in short: the FDA determined that the totality of the scientific evidence supports a qualified health claim on the relationship between magnesium and a reduced risk of high blood pressure in conventional foods and dietary supplements.

PRE-MENSTRUAL SYNDROME - Researchers have found that the combination of magnesium and vitamin B6 has significant effects on reducing anxiety-related premenstrual symptoms (nervous tension, mood swings, irritability, or anxiety). One of the ways in which vitamin B6 may relieve the symptoms of PMS is by increasing cellular magnesium levels.*

KIDNEY STONES - Magnesium citrate has been shown to increase the solubility of calcium oxalate and inhibit both calcium phosphate and oxalate stone formation. Many patients with recurrent oxalate stones show laboratory signs of vitamin B6 deficiency. Vitamin B6 is known to reduce the production and urinary excretion of oxalates.*

DEPRESSION - Vitamin B6 nutritional status has a significant and selective modulatory impact on central production of both serotonin and GABA, neurotransmitters that control depression, pain perception, and anxiety. Vitamin B6 levels are often found to be low in women taking birth control pills or Premarin. It is likely that many millions of people taking Prozac may be suffering depression as a result of low B6 status.*

FATIGUE - An underlying magnesium deficiency, even if 'sub-clinical', can result in chronic fatigue and symptoms similar to chronic fatigue syndrome (CFS). Many chronic fatigue syndrome patients have been shown to have low red blood cell magnesium levels.*

MIGRAINE / TENSION HEADACHES - Several researchers link low magnesium levels with both migraine and tension headaches based on their theories and clinical observations. Reduced levels of magnesium are found in the serum, saliva, and red blood cells of migraine sufferers, which indicates a need for the supplementation because one of magnesium's key functions is the maintenance of blood vessel tone.*

Magnesium is an essential mineral required for energy and protein production, muscular contraction, and proper functioning of enzymes. It is also an important component found in the bone and is necessary for bone formation. In a placebo-controlled study with postmenopausal women, 290mg of magnesium citrate daily led to a 43.7% increase in osteocalcin in the blood (a marker of bone formation). Read more on all the benefits magnesium has to offer.*


See All LifeSource Vitamins Magnesium Products, Articles and Studies: Click Here

Cardiovascular Health

As magnesium is required for muscle contraction, it is no surprise in the amount of evidence showing the benefits of magnesium in heart health. In a prospective study with15 years of follow-up in individuals at risk for coronary artery disease, researchers found that serum magnesium levels greater than 1.8 mEq/L had a 25% decreased risk of stroke. These results were replicated in another study showing that every 100 mg intake of magnesium per day produced an 8% reduction in stroke risk. Further research has also demonstrated intakes more than 345mg/d compared to intakes less than 261mg/d is associated with a lower risk of cardiac death (34% vs. 77%). Other research showed that taking 370 mg/d of magnesium dropped systolic blood pressure 3-4mmHg and diastolic pressure by 2-3mmHg. Even more, one extra serving per day of magnesium-rich foods such as whole grains, vegetables, and nuts will help lower the risk of death from cardiovascular disease by 28%.*

Brain/Psychiatric Health

Magnesium is also necessary for nerve conduction and thus supports brain health. In a placebo-controlled trial, test rats with Alzheimer’s given magnesium performed similarly to normal healthy mice in a series of cognitive tests. In children with ADHD, supplementation with magnesium (60mg/kg/d) reduced hyperactivity and improved attention in school. Furthermore, 500mg/d of magnesium has been shown to decrease Insomnia severity by 14.5% and improve sleep by 8.9%.*

Sugar Control

Research on dairy suggests that magnesium found in dairy may contribute to a lower risk of diabetes. Further research also shows the recommended daily allowance of magnesium (400mg/d) is associated with 71% lower insulin resistance.*

Gastro-Intestinal (G.I.) Health

In a prospective study on men, magnesium intakes above 327mg/d contributed to a 35% reduced risk of colorectal cancer. Other positive results on gastrointestinal health show that every 50 mg/d increase in magnesium intake produced a 5% decreased risk of colorectal cancer. Further benefits have also been observed in a study highlighting a 33% reduced risk of gallstones with intakes meeting recommended daily allowance (400mg/d).*

Lung Health

Magnesium can also improve lung function. In a placebo-controlled study on individuals living with asthma, magnesium supplementation led to a 21% increased control of asthma and an overall 8% improvement in the quality of life. In patients with cystic fibrosis, 300mg of magnesium contributed a 5.6% improvement in the severity of cystic fibrosis.*

Potential applications

Pre-menstrual tension, kidney stones, depression, hypertension, chronic fatigue syndrome (CFS), neuro-muscular/skeletal disorders, migraine, nausea in pregnancy, hyperhomocysteinemia, osteoporosis, diabetic neuropathy, asthma (B6 is needed for tryptophan > serotonin metabolism - known to be disordered in asthmatics).*

Known contraindications

Those with kidney or heart disease should consult their physician before using magnesium supplements. Pregnant and breastfeeding women should not take more than 100 mg of vitamin B6 per day without a doctor's supervision.

LifeSource Vitamins - Magnesium Citrate, shown to help with Premenstrual tension, kidney stones, depression, hypertension, chronic fatigue syndrome (CFS), neuro-muscular/skeletal disorders, migraine, nausea in pregnancy, hyper-homocysteinemia, osteoporosis.*

As with all products like this, before taking magnesium citrate, tell your doctor if you have any other medical conditions, allergies, or if you take other medicines or other herbal/health supplements. Magnesium citrate may not be recommended in some situations.


What other drugs will affect magnesium citrate?

Before taking magnesium citrate, talk to your doctor if you are taking:

• Tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others);
• A fluoroquinolone antibiotics such as ciprofloxacin (Cipro), ofloxacin (Floxin), enoxacin (Penetrex), norfloxacin (Noroxin), sparfloxacin (Zagam), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), and others;
• Penicillamine (Cuprimine);
• Digoxin (Lanoxin, Lanoxicaps); or
• Nitrofurantoin (Macrodantin, Furadantin, others

You may not be able to take magnesium citrate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.


Drugs other than those listed here can also interact with magnesium citrate. Talk to your doctor and pharmacist before taking any over-the-counter or prescription medicines, including herbal products.

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*Disclaimer: None of the above statements have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As always, consult your physician before taking any and all supplements. LifeSource Vitamins. Individual results may vary.

Disclaimer: All the information contained throughout this website is based upon the opinions of the founder of LifeSource Vitamins, Bruce Brightman, and the entire team at LifeSource Vitamins whose relentless research and studies have been ongoing since 1992. Other articles and information are based on the opinions of the authors, who retain the copyright as marked in the article. The information on this site is not intended to replace your health care professional, but to enhance your relationship with them. Doing your own studying and research and taking your health care into your own hands is always best, especially in partnership with your health care professional.

If you are pregnant, nursing, taking medications, or have any medical conditions, always consult your health care professional before taking supplements based on the information on this site.

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