Grape Seed Extract which is high in Oligomeric Proanthocyanidins (OPC’s or PCO’s) is a powerful antioxidant that can reduce the damage done by free radicals, strengthen and repair connective tissue, and promote enzyme activity. OPC’s can also help moderate allergic and inflammatory responses by reducing histamine production.*

Antioxidants
Antioxidants are important protectors of health because they provide electrons that neutralize "free radicals"--molecules with unpaired electrons which have the power to cause degenerative and life-threatening diseases.*

Free radicals are produced from normal oxygen metabolism within the body, and from exposure to certain chemicals, environmental pollutants, sunlight, radiation, burns, cigarette smoke, drugs, alcohol, viruses, bacteria, parasites, dietary fats, and more. The antioxidants known today are vitamins C and E, beta carotene, selenium, bioflavonoids, and bioflavanols.*

• Enhanced capillary strength and vascular function, which helps the heart and decreases: PMS problems, bruising, edema from injury or trauma, varicose veins, leg swelling, and retinopathy.*
• Leukoencephalopathy - As depicted in the movie Lorenzo's Oil.
• Enhanced immune resistance.*
• Increased peripheral circulation, improving vision.*
• Reduced adverse allergic and inflammatory responses.*
• Reduction in skin aging and loss of elasticity.*
• It is bioavailable and immediately absorbed from the stomach into the bloodstream.*
• It is distributed to virtually every organ and tissue, and remains in the body for up to 72 hours.*
• Not only does it neutralize free radicals themselves, but it also conserves and regenerates vitamins C and E. Vitamin E is a powerful free radical scavenger, but it is quickly used up.

See All LifeSource Vitamins Grape Seed Products, Articles, and Studies: Click Here

Anti-Histamine

The anti-histamine action of PCO is mediated by an inhibiting effect on the enzyme histidine decarboxylase which is responsible for the production of histamine. This is enhanced by PCO's ability to block hyaluronidase, the enzyme that facilitates the release of histamine into body tissues.*

Anti-Allergic
This action is related to the antihistamine effect, as well as PCO's ability to strengthen cell membranes of basophils and mast cells, which contain the allergic chemicals, thus preventing over-reaction or hypersensitivity to pollens and food allergens. Many allergy sufferers have reported significant relief using grape seed extract.*

Anti-Ulcer
Ulcers induced or aggravated by stress are known to be related to excessive secretion of histamine in the stomach lining. PCOs help heal ulcers by reducing histamine secretion and by binding to and protecting connective tissue in mucous membranes.*

Cardiovascular Disease
Experimental studies have recently discovered that oxidation of LDL cholesterol is a key factor leading to hardening of the arteries and heart disease. The antioxidant effect of Vitamin E has been shown to be a potent inhibitor of this oxidation—and PCO has been shown to be 50 times more potent than vitamin E. PCO has also been shown to prevent the stickiness of blood platelets that can lead to blood clots and strokes. Patients taking grape seed extract PCO have reported reduced blood pressure and cholesterol levels.*

Recent studies have shown that drinking wine has a protective effect against heart disease (considered the solution to the mystery of how the French population can indulge in a high-fat diet and have one of the world's lowest incidences of heart disease). And in February of 1995, a study published in "Circulation," the journal of the American Heart Association, showed that six glasses of grape juice were as effective as two glasses of wine in preventing heart disease. This study offers convincing evidence that PCO from grapes, rather than the alcohol, provide wine's protective benefits to the circulatory system.*

Certain Cancerous Prevention's
Although not a cure for cancer, experimental evidence has been available for a long time showing that antioxidants greatly reduce the incidence of all types of cancer. One study showed that the risk of developing cancer is 11.4 times greater for those with low levels of the antioxidants vitamin E and selenium. PCO is a more potent antioxidant, and also protects cellular DNA from oxidative damage and cell mutations which can lead to cancer.*

Diabetes Complications
Taking Grape Seed in addition to adding an exercising program has been shown to improve lipid profiles, weight loss, blood pressure, and numerous other diabetic complications. This study is located here: https://www.ncbi.nlm.nih.gov/pubmed/24757634

Teeth and Gums
Dentists and their patients have reported that PCO provides healing and preventive benefits to the teeth and gums, evidently through its anti-inflammatory effects, free radical deactivation, and connective tissue protection.*

Eyes
Clinical studies have shown that antioxidants can halt cataract progression. PCO has a strong affinity for the portion of the retina that is responsible for visual acuity. It prevents free radical damage and reinforces the collagen structures of the retina. In clinical trials of patients with various types of retinal disease, including macular degeneration, all patients given PCO showed significant improvement following therapy. Health professionals monitoring the effects of PCO have reported that it also has helped in the prevention and treatment of glaucoma.*

Skin Care
PCO products help protect the skin from ultraviolet radiation damage that leads to wrinkles and skin cancer. Because it stabilizes collagen and elastin, PCO can help improve the elasticity and youthfulness of the skin. PCO strengthens the connective tissue of the skin and fat chambers. People taking grape seed extract PCO have noticed that it helps tonify their skin and reduce cellulite, stretch marks, and old scars. There is speculation that cellulite may be a sign of bioflavonoid deficiency.*

Nervous System
Some physicians have reported that patients with multiple sclerosis (MS) have improved while taking PCO. MS is a syndrome of progressive destruction and hardening of the myelin sheath that surrounds the nerves. Current research indicates that MS may be caused by an allergic or autoimmune reaction. Many studies have demonstrated that patients with MS have reduced activity levels of the antioxidant enzyme glutathione peroxidase.*

The ability of PCO to reduce the progressive symptoms of MS may be due to its potent antioxidant and anti-allergic qualities. Plus, PCO has the ability to cross the blood-brain barrier, where it may protect the brain's nervous tissue from oxidation. This effect may explain why patients taking PCO often report improved mental clarity.*

Lungs
Asthma and emphysema have also been found to benefit from the use of PCOs. Asthma is largely caused by an allergic reaction within the bronchial tubes that leads to bronchial constriction and excessive mucous excretion. Due to its ability to inhibit histamine and other inflammatory chemicals, PCO has been found effective in the treatment of asthma.*

Grape seed extract PCO has also been found to reduce the coughing, wheezing, weakness, mucous and recurring respiratory infections usually associated with emphysema. Apparently, PCO reduces the inflammation and damage to the air sacs of emphysema patients.*

Grape Seed Extract Enhanced: shown to help capillary strength, vascular function, heart health and decreases PMS problems, bruising, edema from injury or trauma, varicose veins, leg swelling and retinopathy, enhanced immune resistance.*

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*Disclaimer: None of the above statements have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As always, consult your physician before taking any and all supplements. LifeSource Vitamins. Individual results may vary.

Disclaimer: All the information contained throughout this website is based upon the opinions of the founder of LifeSource Vitamins, Bruce Brightman, and the entire team at LifeSource Vitamins whose relentless research and studies have been ongoing since 1992. Other articles and information are based on the opinions of the authors, who retain the copyright as marked in the article. The information on this site is not intended to replace your health care professional, but to enhance your relationship with them. Doing your own studying and research and taking your health care into your own hands is always best, especially in partnership with your health care professional.

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