PS or Phosphatidyl Serine is also referred to as the Essential Brain Nutrient! Phosphatidylserine is a phospholipid that is found in virtually every cell of our bodies but is most highly concentrated in the walls or membranes of brain cells, which have been shown to make up about 70% of its nerve tissue mass. There it aids in the storage, release, and activity of many vital neurotransmitters and their receptors. Phosphatidylserine also aids in cell-to-cell communication. PS is a must-have for maintaining of healthy cognitive functioning over the course of our lives.*

PS - Phosphatidyl Serine is the single most important building block nutrient for healthy, alive, active and functional brain cells.

• PS supports & protects our Brain Functioning processes*
• PS supports the boosting of our Memory and Focus*
• PS levels in the brain naturally decline with age.*
• PS has shown to help with Age-Related Mental Decline*
• PS supports a healthier/sharper mind. Retention of Information.*
• PS supports help with Language Skills in aging adults*
• PS has been shown to fight Cognitive Decline*
• PS has been shown to help with Attention, Memory, Learning Processes and Cognition.*
• PS has been shown to help in Combatting Stress*
• PS has been shown to have a positive effect on Mood.*
• PS can improve Coordination, and as we know as we age this is helpful.*

PS - Phosphatidyl Serine, what we must understand about this supplement is the fact that it is capable of crossing the blood-brain barrier quite easily. Once this happens, Phosphatidylserine binds with neurotransmitters and enables the brain to metabolize glucose more efficiently. This supplement also helps to heighten communication between brain cells. It can increase the fluidity of cell membranes in neurons that had been previously damaged or were suffering signs of age.*

It is at this point these neurons then become rejuvenated and capable of receiving and sending messages at a faster rate again. PS - Phosphatidylserine also enables the brain to more easily restore its supply of the key neurotransmitter Acetylcholine. There is also evidence suggesting that the supplement helps the brain to produce more Dopamine, another key neurotransmitter which is important in a variety of cognitive processes such as mood. *

See All LifeSource Vitamins Phosphatidyl Products, Articles, and Studies: Click Here

The FDA: The FDA has even authorized the use of labels stating, “consumption of phosphatidylserine may reduce the risk of dementia and cognitive dysfunction in the elderly.” However, the FDA holds that there is little scientific evidence supporting this claim. They approved the label because of the large body of scientific evidence, spanning three decades, supported this benefit of PS supplementation.

Study #1: One study where healthy, young adults were given a dose of phosphatidylserine for 2 weeks experienced a whopping20% improvement in processing speed,accuracy by responding with 13% more correct answers, and 39% less wrong answers compared to a placebo. In this study, PS affected every measure of cognitive function. This is astonishing really.

Study #2: In a double-blind placebo-controlled multicenter study of 425 individuals, daily supplementation of phosphatidylserine over six months resulted in statistically significant support of behavioral and cognitive parameters.

Study #3: A six-month study of 40 individuals, phosphatidylserine supplementation enhanced cerebral metabolism and outcomes of cognitive training. These findings are consistent with earlier studies.

Study #4: In a placebo-controlled investigation of 149 subjects, the group receiving phosphatidylserine scored higher than placebo in performance tests related to memory tasks of daily life.

Study #5: In a trial of 35 subjects, those receiving phosphatidylserine exhibited behavioral support after six months.

Most supplements out there have just 100mg of Phosphatidylserine: LifeSource Vitamins has a unique blend to ensure absorption:

Phosphatidyl serine complex 500 mg *

Phosphatidylserine 100 mg *

Phosphatidylcholine 55 mg *

Phosphatidylinositol 10 mg *

Phosphatidylethanolamine 20 mg *

Linolenic acid 10 mg *

Linoleic acid 85 mg *

Oleic acid 15 mg *

Palmitic acid 27 mg *

Stearic acid 6 mg *

Capric acid 51 mg *

Caprylic acid 120 mg *

Read some more info provided by the good people at: Natural News.com

Phosphatidylserine plays a major role in determining the integrity and fluidity of brain cell membranes. Normally, the brain can manufacture sufficient levels of phosphatidylserine, but if there is a deficiency of folic acid and vitamin B12, or of essential fatty acids, the brain may not be able to make sufficient phosphatidylserine. Low levels of phosphatidylserine in the brain are associated with impaired mental function and depression in the elderly.
Encyclopedia Of Natural Medicine by Michael T Murray MD Joseph L Pizzorno ND, page 228

Low levels of phosphatidylserine, a type of lipid, in the brain are commonly associated with memory loss. This is an important brain nutrient and is essential for effective neurotransmission. Smart Medicine For Healthier Living by Janet Zand LAc OMD Allan N Spreen MD CNC

James B LaValle RPh ND, page 406

Low levels of phosphatidylserine in the brain are associated with impaired mental function and depression in the elderly.

Encyclopedia of Nutritional Supplements by: Michael T Murray ND, page 356

Once we reach middle age, phosphatidylserine and other important brain chemicals decline, which is one reason why our brains don't work as efficiently. There is good evidence that taking phosphatidylserine supplements can help restore brainpower.

Earl Mindell's Supplement Bible by Earl Mindell RPh Ph.D., page 120

Human-based clinical studies

Alzheimer's disease and senile patients have also experienced benefits following treatment with phosphatidylserine. Doses of 400 mg per day led to significant, short-term neuropsychological improvements in such patients relative to controls. The administration of 300 mg per day for eight weeks led to significant clinical improvements in patients with mild primary degenerative dementia. In another study, Alzheimer's patients received 100 mg per day of bovine cortex phosphatidylserine for twelve weeks. Results showed the treatment improved several cognitive measures relative to controls. Animal trials have produced similar results. Phosphatidylserine has promise for cancer and heart disease as well.

Ultimate Anti-Aging Program by Gary Null Ph.D., page 183

Phosphatidylserine is one of the most abundant phospholipids in the brain. Its primary role is to help relay chemical messages from brain cell to brain cell. Studies have shown that phosphatidylserine supplements can have a significantly positive effect on brain function. In one recent study, 149 healthy men and women, 50 to 70 years of age, were all diagnosed with normal age-associated memory impairment, the kind of forgetfulness we all experience as we grow older. Participants were given 100 mg of phosphatidylserine (PS) daily for 12 weeks, or a placebo. Those taking the PS noted significant improvements in their ability to do normal tasks, such as recall telephone numbers and names and faces. Those who took the placebo showed virtually no change.

Earl Mindell's Supplement Bible by Earl Mindell RPh Ph.D., page 261

Parkinson's Disease -This article notes that clinical and experimental research indicates phosphatidylserine prepared from cow's brain can have positive effects on cerebral changes involved in the symptoms of Alzheimer's type senile dementia among patients with Parkinson's disease.

The Clinician's Handbook of Natural Healing by Gary Null Ph.D., page 122

In a 1991 study of phosphatidylserine among people aged 50 to 75, doctors found positive results when they used 100-milligram doses of PS, three times daily. Researchers found a 30 percent improvement in cognitive function that included memory, learning, recalling names, faces, and numbers. They also found that some people with the worst memory impairment were more likely to respond positively to PS.

Natural Physicians Healing Therapies by Mark Stengler ND, page 363

Alzheimer's Disease study results showed that phosphatidylserine administered in doses of 400 mg per day led to significant, short-term neuropsychological improvements in patients with Alzheimer's disease relative to controls.

The Clinician's Handbook of Natural Healing by Gary Null Ph.D., page 117

The primary use of phosphatidylserine is in the treatment of depression and/or impaired mental function in the elderly. Very good results have been obtained in numerous double-blind studies. Statistically, significant improvements were noted in the phosphatidylserine-treated group in mental function, mood, and behavior. In a double-blind study of depressed elderly patients, phosphatidylserine improved depressive symptoms, memory, and behavior.

Encyclopedia of Nutritional Supplements by Michael T Murray ND, page 357

Phosphatidylserine (PS) belongs to a special category of fat-soluble substances called phospholipids, which are essential components of cell membranes. PS is found in high concentrations in the brain and may help preserve, or even improve, some aspects of mental functioning in the elderly when taken in the amount of 300 mg per day for 3 to 6 months, according to double-blind research. Placebo-controlled and double-blind studies have shown mild benefits from PS supplementation when used in the amount of 300 mg per day for 3 to 12 weeks in patients with early Alzheimer's disease. In one double-blind study, the improvement on standardized tests of mental functioning averaged approximately 15%. Continued improvement has been reported up to 3 months beyond the end of the supplementation period.

The Natural Pharmacy by Schuyler W Lininger, page 264

Oral administration of 300 mg per day of soybean transphosphatidylated phosphatidylserine can improve and/or prevent senile dementia in humans.

The Clinician's Handbook Of Natural Healing by Gary Null Ph.D., page 120

Phosphatidylserine supplementation in animal studies and human clinical trials has significantly improved acetylcholine release, memory, and age-related brain changes.

Encyclopedia of Nutritional Supplements by Michael T Murray ND, page 356

Double-blind Randomized Controlled Study of phosphatidylserine in Senile Demented Patients. This double-blind, placebo-controlled study examined the effects of 300 mg per day of phosphatidylserine for 30 days on cognitive, affective and behavioral symptoms of elderly women with depressive disorders. Results showed that patients receiving phosphatidylserine experienced improvements with respect to memory, behavior, and depressive symptoms relative to controls.

The Clinician's Handbook of Natural Healing by Gary Null Ph.D., page 119

An impressive volume of research shows that phosphatidylserine, another modified amino acid benefits acetylcholine deficiencies. We often recommend phosphatidylserine in our clinic when a patient is diagnosed with a memory disorder, early dementia, or depression. Multiple sclerosis patients may respond to phosphatidylserine as well.

The Edge Effect By Eric R Braverman MD, page 112

Brain Function -- Results of this study showed that patients suffering from chronic cerebral decompensation experienced improvements in mnesic and neuropsychic symptomatology following phosphatidylserine administration for 60 days.

The Clinician's Handbook Of Natural Healing by Gary Null Ph.D., page 119

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*Disclaimer: None of the above statements have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As always, consult your physician before taking any and all supplements. LifeSource Vitamins. Individual results may vary.

Disclaimer: All the information contained throughout this website is based upon the opinions of the founder of LifeSource Vitamins, Bruce Brightman, and the entire team at LifeSource Vitamins whose relentless research and studies have been ongoing since 1992. Other articles and information are based on the opinions of the authors, who retain the copyright as marked in the article. The information on this site is not intended to replace your health care professional, but to enhance your relationship with them. Doing your own studying and research and taking your health care into your own hands is always best, especially in partnership with your health care professional.

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