5-HTP 100mg + Valerian Root - LifeSource Vitamins5-HTP + Valerian Root — Sleep & Mood Support — Promotes Relaxation & Emotional Balance*
Feel calm in the evening and clearer by morning — LifeSource Vitamins 5-HTP + Valerian pairs two time-tested botanicals to support deeper, more restorative sleep and balanced mood.* 5-HTP from Griffonia simplicifolia nourishes healthy serotonin pathways, while Valerian Root (Valeriana officinalis) supports GABA activity for relaxation without next-day grogginess.* Crafted in FDA-registered, GMP-certified facilities and independently 3rd-party tested for identity, purity, and potency.
Research Promise. At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep guidance aligned with credible science*.
Clinically Studied Benefits (Human Evidence)
- Enhances sleep quality — 5-HTP and Valerian have been studied for sleep latency and REM parameters. (NIH/PubMed — 2020)
- Supports balanced mood — 5-HTP research explores effects on mood ratings; Valerian contributes calming support. (NIH/PubMed — Turner EH, 2006)
- Helps ease everyday tension — Trials report favorable changes on stress/relaxation scales with serotonergic and GABAergic support. (NIH/PubMed — Jangid P, 2013)
- Supports faster sleep onset — Valerian has been evaluated for time-to-sleep outcomes; 5-HTP complements sleep architecture. (NIH/PubMed — Soulairac A, 2004)
- Sleep quality — meta-analysis signal — Systematic reviews of valerian suggest benefit on perceived sleep quality (with study-quality caveats). (NIH/PubMed — Bent S, 2006)
Additional / Promising Evidence
- Synergy & sleep architecture — Exploratory work examines combined botanicals and sleep-cycle quality. (NIH/PubMed — 2020)
- Calm & relaxation — Valerian has long been reviewed for its role in relaxation responses and perceived sleep quality. (NIH/PubMed — 2020)
- Appetite regulation (5-HTP) — Investigated for supporting calorie control in diet programs. (NIH/PubMed — Ceci F, 1992)
University / Academic Context
- National University of Singapore (2024) — Clinical trial in older adults reported improved sleep quality with 5-HTP, with favorable shifts in gut-microbiome composition.
- University of Utah (2024) — Ongoing registered trial is investigating 5-HTP plus creatine on mood and serotonin-related biomarkers.
- Duke University (2019) — Preclinical work on slow-release 5-HTP suggests potential when combined with serotonergic support strategies.
- Southwest Medical University (2022) — Mouse model showed oral 5-HTP supported gut-brain axis balance with improvements in depressive-like behaviors.
- Yale University — Research exploring 5-HTP’s effects on attention and interactions with serotonin-receptor pathways.
- University of California, Irvine — Programs include investigations of traditional botanicals for sleep support.
Global Evidence & Authoritative Reviews
- Evidence synthesis — Academic reviews note that larger, high-quality RCTs are still needed; current human studies support roles in sleep regulation and mood support via serotonin pathways.
- Appetite/fullness — Evidence suggests 5-HTP may increase satiety and support calorie control in structured programs.
Institutional Monitoring. We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science*.
Key Ingredients
- 5-Hydroxytryptophan (5-HTP) — Serotonin precursor studied for mood and sleep outcomes. (NIH/PubMed — Turner EH, 2006)
- Valerian Root Extract (Valeriana officinalis) — Traditionally used to promote relaxation and healthy sleep. (NIH/PubMed — 2020)
Brief Benefit Bullets
- Promotes deep, restful sleep and healthy sleep patterns*
- Supports mood balance and emotional well-being*
- Helps ease everyday stress and tension*
- 3rd-party tested for purity and potency*
Suggested Use
Adults: Take 1–2 capsules 30–60 minutes before bedtime on an empty stomach, or as directed by a healthcare professional. Start with 1 capsule to assess tolerance. For daytime mood support, may be taken earlier in the day as needed. Do not exceed recommended dosage. Consult a physician before use if pregnant, nursing, taking medications (especially SSRIs, MAOIs, or other serotonergic agents), or if you have a medical condition. Keep out of reach of children.*
Product Specifications
- Form — Vegetarian Capsules
- Quality — Non-GMO, gluten-free, dairy-free, soy-free, vegan; 3rd-party tested*
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.
LifeSource Vitamins 5-HTP + Valerian Root — Supports sleep quality, mood balance, and stress relief. Non-GMO, vegan & 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*