32 Arthritis Relief & Joint Rebuilder Nutrients — Tablets — Promotes Joint Comfort & Mobility*
LifeSource Vitamins Arthritis Relief & Joint Rebuilder delivers a comprehensive blend of 32 ingredients—including Glucosamine, Chondroitin, MSM, Hyaluronic Acid, Omega-3s, Boswellia, Turmeric/Curcumin, Ginger, White Willow Bark, Quercetin, Grape Seed Extract, Citrus Bioflavonoids, plus essential vitamins & minerals—to support joint comfort, mobility, and cartilage health.* Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity, potency & label accuracy.*
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from leading health organizations and insights from top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
Group 1 — Core Joint Rebuilders (structure/function & lubrication)
• Glucosamine Sulfate — Evidence mixed overall; some trials show improved pain/function in knee OA, especially sulfate form and longer use. (NCCIH overview; NEJM GAIT Trial)
• Chondroitin Sulfate — May reduce pain and improve function; some RCTs suggest structure-modifying effects. (NCCIH; Ann Rheum Dis meta-analysis)
• Glucosamine + Chondroitin (combo) — Subgroup with moderate-to-severe pain benefited in GAIT; results otherwise mixed. (GAIT; Cochrane review)
• MSM (methylsulfonylmethane) — RCTs report improvements in pain and function for knee OA. (J Orthop Res 2006; Complement Ther Med 2011)
• Hyaluronic Acid — Strongest evidence for intra-articular HA; oral forms show emerging/mixed data. (Cochrane IA HA; Oral HA pilot)
Group 2 — Anti-Inflammatory Botanicals & Proteolytic Enzymes
• Boswellia serrata (AKBA/5-Loxin) — Multiple trials show reduced knee OA pain & improved function. (Arthritis Res Ther; Int J Med Sci; Arthritis Foundation)
• Turmeric/Curcumin — Meta-analyses show benefit vs placebo and non-inferiority to NSAIDs for knee OA pain, with fewer AEs. (Systematic review 2019; Inflammation markers meta-analysis)
• Ginger — RCTs/meta-analyses show modest improvements in pain/function. (Osteoarthritis Cartilage 2015)
• White Willow Bark (salicin) — Traditional analgesic; evidence for musculoskeletal pain. (NCCIH)
• Devil’s Claw (Harpagophytum) — Reviews suggest benefit for OA/low-back pain. (Cochrane review)
• Cat’s Claw (Uncaria tomentosa) — Small RCT adjunct in RA showed reduced pain/swelling. (J Rheumatol 2001)
• Bromelain — Proteolytic enzyme with anti-inflammatory/analgesic signals in OA. (EBM Complement Alternat Med)
Group 3 — Oils, Bioflavonoids & Antioxidants
• Omega-3 (EPA/DHA) Fish Oil — Cochrane review in RA: reduced joint tenderness and NSAID use; supports inflammatory balance. (Cochrane RA review; Harvard Nutrition Source)
• GLA (Borage/Evening Primrose) — Evidence for RA pain/swelling reduction at adequate doses. (Systematic review; Rheumatology review)
• Quercetin — Small RCTs suggest benefit in RA symptom scores/oxidative stress. (Phytother Res 2018)
• Grape Seed Extract (OPCs) — Antioxidant/anti-inflammatory signals supportive to joint health. (Nutr Res 2010)
• Citrus Bioflavonoid Complex — Review supports antioxidant/anti-inflammatory activity. (Molecules review)
Group 4 — Vitamin & Mineral Cofactors (cartilage, collagen, antioxidant defense)
• Vitamin C — Required for collagen synthesis; deficiency impairs cartilage/ligament integrity. (NIH/ODS — Vitamin C)
• Vitamin D — Bone & muscle support; low levels associate with worse OA pain/function; supplementation evidence mixed. (NIH/ODS — Vitamin D)
• Vitamin E — Antioxidant; mixed symptom outcomes in OA. (NIH/ODS — Vitamin E)
• B-Complex (Niacinamide, B6, Pantothenic Acid, etc.) — Energy metabolism & tissue support; niacinamide small trial showed mobility benefits in OA. (Ann Intern Med 1996)
• Calcium, Magnesium — Bone & muscle cofactors. (NIH/ODS — Calcium; NIH/ODS — Magnesium)
• Zinc, Copper, Selenium — Enzymatic/antioxidant roles (e.g., SOD, GPx) relevant to cartilage & inflammation balance. (NIH/ODS — Zinc; NIH/ODS — Copper; NIH/ODS — Selenium)
• Boron — Trace element linked to bone/joint health; small clinical/observational signals. (Environ Health Perspect)
Additional Studies Showing Promising Benefits*
• Licorice (Glycyrrhiza) — Anti-inflammatory constituents (glycyrrhizin); supportive but limited human joint data—monitor blood pressure/potassium with high intake. (Review)
• Yucca — Traditional use for joint comfort; limited human data. (American Botanical Council)
• Horsetail (silica) — Connective tissue support; human data limited. (ABC)
• Grape Seed Extract / Quercetin — Antioxidant support with emerging anti-inflammatory signals. (Nutr Res; Phytother Res)
• Curcumin adjunct — Non-inferiority vs NSAIDs for knee OA pain with improved tolerability in several trials. (Systematic review)
University / Academic Context*
• Harvard T.H. Chan — Omega-3 evidence synopses for inflammation/joint health. (Harvard Nutrition Source)
• OSU — Linus Pauling Institute — Micronutrient roles in inflammation and connective tissue (Vitamin C, D, E, Selenium, etc.). (LPI Micronutrient Center)
• Tufts & Boston University — Academic reviews on diet, weight, and OA symptom trajectories. (PMC review set)
• Cleveland Clinic — Evidence summaries on ginger/turmeric for joint comfort. (Cleveland Clinic)
Global Evidence & Authoritative Reviews*
• NCCIH — Glucosamine/Chondroitin, Willow Bark. (NCCIH G+C; NCCIH Willow Bark; NCCIH Shark Cartilage)
• Cochrane — Systematic reviews for intra-articular hyaluronic acid, omega-3s in RA, glucosamine/chondroitin evidence. (IA HA; Omega-3 RA; Cochrane Library)
• Arthritis Foundation — Ingredient summaries & guidance for OA/RA self-care. (Arthritis.org)
• American Botanical Council — Monographs & HerbClip evidence summaries for joint-related botanicals. (ABC)
Brief Benefit Bullets
• Helps relieve joint discomfort for easier movement*
• Supports cartilage integrity & joint lubrication*
• Promotes mobility & flexibility for active living*
• Backed by clinical research across multiple ingredients*
• Provides antioxidant & anti-inflammatory support*
3rd-party lab tested for identity, potency & purity
Suggested Use
Adults take 4 tablets daily with meals—preferably 2 in the morning and 2 in the evening—or as directed by your healthcare professional. Consistent use for 2–3 months supports best results. Do not exceed recommended dose. If pregnant, nursing, taking medications (especially anticoagulants), or have a medical condition, consult your physician.*
Product Specifications
• Count — 100 tablets (25 servings)
• Key actives per serving — Glucosamine Sulfate, Chondroitin Sulfate, MSM, Hyaluronic Acid, Omega-3 Fish Oil (EPA/DHA), Boswellia serrata, Turmeric/Curcumin, Ginger, White Willow Bark, Bromelain, Quercetin, Grape Seed Extract, Citrus Bioflavonoids, Vitamins A/C/D/E/B-complex, Calcium, Magnesium, Zinc, Selenium, Copper, Boron, and more (see label)
• Allergens — Contains fish (fish oil) and may contain shellfish sources (glucosamine/chondroitin)
• Free From — Non-GMO; gluten-free; dairy-free*
• Quality — Third-party tested for identity, potency & purity
3rd-Party Testing: Every batch is independently verified for identity, potency, heavy metals & microbial purity. See our testing.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.
33 Nutrient Comprehensive joint formula with Glucosamine, Chondroitin, MSM, Hyaluronic Acid, Omega-3s, Boswellia, Curcumin & antioxidants — research-referenced (NIH/NCCIH/Cochrane/Arthritis Foundation) and third-party tested.*
