LifeSource Vitamins Artichoke Liquid Extract — Antioxidant, Bile & Liver Support*
This liquid extract uses Organic Artichoke Leaf (Cynara scolymus) standardized by traditional herb-strength methods. Artichoke leaf is naturally rich in cynarin, chlorogenic/caffeoylquinic acids, luteolin, and quercetin—polyphenols studied for antioxidant, choleretic (bile-flow), and hepatoprotective activity. Human data and authoritative reviews indicate potential support for healthy liver enzymes (ALT/AST), lipid balance, digestive comfort, and endothelial/vascular function.*
Research Promise:At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from leading health organizations and top global universities to help keep our guidance aligned with credible science.*
Clinically Studied Benefits (with research)
• Liver enzymes (ALT/AST) — Meta-analysis and RCTs report significant reductions in elevated ALT/AST after artichoke leaf extract (often ≥500 mg/day for 6–8 weeks). (PubMed)
• NAFLD support — Randomized trials in non-alcoholic fatty liver report improved liver enzymes and steatosis indices with artichoke supplementation. (NIH/PMC)
• Choleretic action (bile flow) — Traditional herbal use supported by human evidence of improved biliary parameters and dyspepsia symptoms. (EMA HMPC Monograph)
• Total & LDL cholesterol — Double-blind trials show modest LDL and total-cholesterol reductions vs placebo with artichoke leaf extract. (Bundy 2008, Phytomedicine; Englisch 2000/2001)
• Functional dyspepsia — Prospective studies report improvements in global dyspepsia scores and well-being with artichoke leaf extract. (PubMed)
• Blood pressure/vascular function — Polyphenol-rich artichoke preparations improved flow-mediated dilation and modest blood-pressure endpoints in small trials. (MDPI Biology 2025 review)
• Glycemic markers — Trials in metabolic risk groups note favorable changes in fasting glucose/insulin resistance alongside lipid and enzyme shifts. (PubMed review)
• Antioxidant capacity — Human supplementation elevates plasma antioxidant capacity and reduces oxidative-stress markers. (PubMed review)
• GI comfort — Open-label and controlled studies show improved abdominal discomfort and bloating with standardized leaf extract. (PubMed)
• Quality-of-life indices — Patients report better global well-being with artichoke vs baseline/placebo in digestive/lipid studies. (Phytomedicine RCT)
• Safety/tolerability — Trials generally report good tolerability without serious adverse effects at studied doses. (Phytomedicine; EMA HMPC)
• Mechanistic (human corroboration) — Leaf polyphenols (cynarin, chlorogenic acids) are linked to bile stimulation, HMG-CoA-reductase modulation, antioxidant defense and ACE-pathway effects. (NIH/PMC review)
Additional Studies Showing Promising Benefits*
• Fatty-liver indices* — Pilot NAFLD data show improvements in hepatic fat scores and inflammatory markers with artichoke. (NIH/PMC)
• Post-prandial lipids* — Polyphenols may blunt post-meal triglyceride/oxidative responses. (PubMed review)
• Endothelial nitric-oxide support* — Chlorogenic/caffeoylquinic acids demonstrate vasodilatory effects that may aid FMD. (MDPI review)
• Digestive comfort & bile flow* — European traditional use recognized for dyspeptic complaints. (EMA HMPC)
• Oxidative-stress pathways* — Human/clinical-adjacent data show enhanced antioxidant enzyme activity after artichoke intake. (PubMed review)
• Metabolic wellness* — Small trials suggest favorable changes in weight parameters when combined with diet/lifestyle. (NIH/PMC)
University / Academic Context*
• Linus Pauling Institute (OSU) — Highlights polyphenol-driven antioxidant and vascular mechanisms relevant to hepatic & cardiometabolic health. (OSU LPI)
• Harvard/Cleveland Clinic — Educational reviews discuss evidence for plant polyphenols and bile-supportive botanicals in metabolic and liver wellness. (Cleveland Clinic)
Global Evidence & Authoritative Reviews*
• EMA HMPC — Approves traditional use of artichoke leaf for digestive/biliary support. (EMA)
• NCCIH/NIH & PMC — Broad evidence summaries on botanicals and polyphenols for metabolic and antioxidant roles. (NCCIH; PMC)
• Cochrane & clinical reviews — Assess herbal interventions for dyspepsia/metabolic risk; call for larger, longer RCTs. (Cochrane)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Oregon State University’s Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to keep guidance aligned with credible science.*
Brief Benefit Bullets
• Polyphenol-rich artichoke leaf for liver & bile support*
• Helps maintain healthy ALT/AST & lipid balance (human trials)*
• Antioxidant support from cynarin, chlorogenic acids, luteolin & quercetin*
• May aid digestive comfort & post-meal wellness*
3rd-party lab tested for identity, potency & purity
Suggested Use
Shake well. Take 30 drops (≈1 mL) in a small amount of water or juice, 1–3 times daily with food, or as directed by your healthcare professional. Use consistently for 4–8 weeks to assess benefit. Do not use if you have bile duct obstruction, gallstones, or allergy to Asteraceae. If pregnant, nursing, or taking medications, consult your physician.*
Product Specifications
• Serving Size — 30 drops (1 mL)
• Servings Per Container — 30
• Herb Weight Equivalence — 500 mg per serving
• Herb Strength Ratio — 1:2 (fresh-herb equivalent)
• Active Ingredient — Organic Artichoke Leaf (Cynara scolymus)
• Other Ingredients — Deionized water; grain alcohol 45–55% by volume
• Free From — Artificial colors/flavors; gluten; dairy; soy*
• Form — Fast-absorbing liquid extract
• Quality — Manufactured in FDA-registered, GMP-certified facilities; third-party tested for identity, potency & purity
3rd-Party Testing: Every batch is independently verified for identity, potency, heavy metals & microbial purity. See our testing.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Artichoke Liquid Extract — organic Cynara leaf for liver enzymes, bile flow, lipids & antioxidant support. 1 mL (30 drops) per serving; 30 servings. Label-true; third-party tested. Clinically Studied Ingredients — NIH/PMC/EMA references!*
