Betaine HCl + Pepsin — Targeted Digestive Support*
This formula pairs Betaine Hydrochloride (HCl) with an acid-stable fungal protease (“fungal pepsin” from Aspergillus niger) in veggie capsules to support healthy gastric acidity, promote efficient protein digestion at mealtime, help maintain optimal stomach pH for nutrient breakdown, support comfortable digestion after protein-rich meals, promote nutrient absorption for pH-sensitive compounds, help maintain digestive comfort, provide enzymatic support for macronutrient metabolism, support traditional digestive wellness applications, promote overall gastrointestinal balance, help maintain comfort during daily meals, and support comprehensive digestive health* — while respecting acid-stable enzyme synergy. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity and potency by LifeSource Vitamins.
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible, evidence-based science.*
Clinically Studied Benefits
✓ Supports rapid gastric re-acidification* — Single doses of betaine HCl quickly lowered elevated gastric pH in volunteers with induced hypochlorhydria in clinical studies.*
NIH/PMC — Heidelbaugh J, 2013
✓ Promotes improved exposure of pH-dependent compounds* — Re-acidifying the stomach with betaine HCl increased exposure of a weakly basic drug with pH-dependent solubility in human trials.*
NIH/PMC — Williams J, 2014
✓ Helps maintain meal-time gastric pH dynamics* — Human work evaluated BHCl during fed conditions and effects on post-meal gastric pH.*
NIH/PubMed — Derakhshan M, 2020
✓ Supports protein digestion with acid-stable protease* — Acid-stable proteases from Aspergillus niger (An-PEP/aspergillopepsins) actively digest dietary proteins in gastric pH; human studies show enhanced gluten protein breakdown.*
NIH/PMC — Tack J, 2015
Additional / Promising Evidence
✓ May support acid-stable enzyme activity by design* — A. niger aspartic proteases are active and stable under acidic gastric conditions in biochemical and structural work.*
NIH/PubMed — Bhattacharya S, 2019
✓ Contributes to practical dosing context* — Reviews outline fed/fasted timing and considerations for BHCl use.*
NIH/PMC — Hwang C, 2016
✓ Supports case-level digestive symptom improvement* — BHCl + pepsin use before protein meals improved symptoms and weight in an individual case.*
NIH/PubMed — Kim H, 2024
✓ May support gut barrier and microbiome in stress models* — Betaine supported intestinal morphology and microbiota in preliminary studies.*
NIH/PMC — Wu Q, 2018
University-Led & Academic Studies
✓ Supports enzyme characterization research* — Academic work on A. niger protease kinetics and substrate handling.*
NIH/PubMed — Bhattacharya S, 2019
✓ Promotes digestive physiology context* — University-led reviews describe gastric pH dynamics and nutrient absorption challenges.*
NIH/PMC — Hwang C, 2016
Global Evidence & Reviews
✓ Confirms NIH Office of Dietary Supplements overview* — Fact sheet on dietary supplements and digestive aids.*
NIH/ODS — 2024
✓ Supports NCCIH complementary digestive research* — Overview of complementary digestive support approaches.*
NCCIH — 2024
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients (per serving)
-
Betaine HCl* — 1,296 mg — Supports healthy stomach acidity for digestion and nutrient absorption.*
-
Acid-Stable Protease (300 SAPU, Fungal Pepsin from Aspergillus niger)* — 300 mg — Supports efficient protein breakdown in gastric pH.*
Brief Benefit Bullets
- Supports healthy stomach acidity for digestion*
- Helps break down dietary proteins with acid-stable protease*
- Backs nutrient absorption for pH-sensitive compounds*
- Designed for mealtime digestive support*
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3rd-party lab tested for identity, potency & purity
Suggested Use
See product label for full instructions, or as directed by your healthcare professional. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
- Serving Size — 2 Veg Capsules
- Servings Per Container — 60
- Betaine HCl — 1,296 mg**
- Acid-Stable Protease (300 SAPU, Fungal Pepsin from Aspergillus niger) — 300 mg**
- Form — Easy-to-swallow vegetarian capsules
- Free From — Non-GMO, gluten-free; not manufactured with yeast, soy, milk, egg, fish, shellfish, tree nuts, or sesame
- Quality — Third-party tested for identity, potency & purity
- Note — Natural color variation may occur
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Betaine HCl + Pepsin — digestive support for protein breakdown, nutrient absorption & gastric pH balance. Clinically Studied Ingredients — NIH/PubMed!*
