Cascara Sagrada 500 mg — 100 Capsules — Traditional Digestive Regularity Support*
Our Cascara Sagrada combines aged bark of Rhamnus purshiana in vegetarian capsules to support occasional digestive regularity, promote short-term intestinal motility, help maintain natural bowel function during occasional irregularity, support gentle stimulant laxative effects, promote water balance in the colon, provide time-honored botanical wellness support, support peristalsis via anthraquinone glycosides, promote occasional elimination comfort, support traditional herbal digestive routines, promote brief-use regularity aid, and support overall GI wellness* — while respecting traditional herbal use. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity and potency by LifeSource Vitamins.
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Supports occasional regularity as a stimulant laxative* — Cascara sagrada acts via anthraquinone glycosides to influence intestinal motility and water/electrolyte balance for short-term constipation relief.*
NIH/LiverTox — Cascara Overview
✓ Promotes short-term intestinal motility and peristalsis* — Anthraquinone derivatives stimulate colonic smooth muscle and reduce water reabsorption in mechanistic and clinical reviews.*
NIH/LiverTox — Mechanism Summary
✓ Helps maintain natural bowel function in occasional use* — Recognized for brief-duration support alongside lifestyle measures like fiber and fluids.*
NIH/NCCIH — Cascara Sagrada
✓ Supports gentle stimulant effects for occasional constipation* — Acts locally in the colon to promote stool evacuation in authoritative overviews.*
NIH/LiverTox — Laxative Action
✓ Promotes time-limited regularity support* — Recommended for short-term use only to avoid potential dependence or imbalance.*
NIH/NCCIH — Usage Guidance
✓ Supports anthraquinone-mediated water balance in colon* — Inhibits reabsorption of electrolytes and water for softer stools in short-term contexts.*
NIH/LiverTox — Anthraquinone Effects
✓ Provides traditional botanical aid for occasional irregularity* — Historical and review evidence supports prudent, intermittent application.*
NIH/NCCIH — Traditional Use
✓ Supports onset of effects within hours for short-term needs* — Stimulant action promotes bowel movement in clinical safety contexts.*
NIH/LiverTox — Onset Profile
Additional / Promising Evidence
✓ Shows mechanistic support for peristalsis stimulation* — Anthraquinones act on colonic nerves to enhance motility in reviews.*
NIH/LiverTox — Mechanism
✓ Promotes short-duration use with lifestyle integration* — Combined with fiber/fluids/activity for better regularity outcomes.*
NIH/NCCIH — Recommendations
✓ Contributes to occasional stool frequency support* — Anthraquinone derivatives reduce water reabsorption in mechanistic evidence.*
NIH/LiverTox — Water Balance
✓ Supports prudent intermittent application* — Emphasized in safety overviews to minimize risks.*
NIH/NCCIH — Safety Context
✓ May aid brief-use digestive wellness routines* — Traditional botanical role in short-term regularity.*
NIH/LiverTox — Traditional Overview
✓ Aligns with guidance for time-limited botanical laxatives* — Reviews stress consultation for persistent symptoms.*
NIH/NCCIH — Use Advice
University-Led & Academic Studies
✓ Supports botanical laxative mechanisms in academic resources* — Oregon State University – Linus Pauling Institute discusses anthraquinone constituents for regularity.*
NIH-indexed — Linus Pauling Institute Overview
✓ Promotes adjunct strategies for digestive regularity* — Harvard and Johns Hopkins resources outline nonpharmacologic approaches including botanicals.*
NIH-indexed — Academic Summaries
Global Evidence & Reviews
✓ Confirms short-term occasional use safety overview* — NIH/NCCIH summarizes mechanism, traditional role, and prudent application.*
NIH/NCCIH — Cascara Sagrada
✓ Supports stimulant botanical evidence in reviews* — Authoritative sources emphasize time-limited use and consultation.*
NIH/NCCIH — Global Context
✓ Aligns with safety and mechanism summaries* — Reviews highlight anthraquinone action for occasional support.*
NIH/LiverTox — Evidence Overview
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
-
Cascara Sagrada Bark (Rhamnus purshiana)* — 500 mg per capsule — Aged bark providing anthraquinone glycosides for traditional occasional regularity support.*
Brief Benefit Bullets
- Time-honored, plant-based support for occasional regularity*
- Aged bark of Rhamnus purshiana (cascara sagrada)*
- Non-GMO; vegetarian capsules
-
3rd-party lab tested for identity, potency & purity
Suggested Use
See product label for full instructions, or as directed by a healthcare professional. For occasional use only; do not use for more than 7 consecutive days. If pregnant or nursing, have a medical condition, or are taking medications, consult your physician.*
Product Specifications
Serving Size — 1 Capsule
Servings Per Container — 100
Amount Per Serving — Cascara Sagrada Bark (Powder) 500 mg (Rhamnus purshiana)
Other Ingredients — Vegetarian cellulose capsules
Form — Vegetarian capsules
Quality — Third-party tested for identity, potency & purity
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Cascara Sagrada 500 mg — 100 capsules; traditional botanical for occasional regularity; vegetarian capsules; Non-GMO; 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
