Cayenne 500 mg — 90 Capsules — Metabolism & Circulation Support*
Cayenne (Capsicum annuum) is traditionally used to support circulation, metabolic rate, and digestive comfort.* Each vegetarian capsule provides 500 mg cayenne fruit. Capsaicinoids (e.g., capsaicin) have been studied for thermogenesis, appetite control, and cardio-metabolic support.* Produced in FDA-registered, GMP-certified facilities and
3rd-party lab tested for purity, potency & label accuracy.*
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
• Thermogenesis & Energy Expenditure — Capsaicin/capsinoids increase energy expenditure and fat oxidation in human studies. (NIH/PMC — Ludy, 2011; NIH/PMC — Josse, 2010)
• Weight-Management Markers (modest) — Meta-analyses report small, significant effects on body weight/BMI/waist circumference. (NIH/PubMed — Zhang, 2023; Europe PMC — Whiting, 2013)
• Appetite Control — Capsaicin/capsinoids help reduce hunger and increase satiety in controlled settings. (NIH/PubMed — Janssens, 2014; NIH/PMC — Rogers, 2018)
• Digestive Support — Evidence for stimulated digestive secretions and GI comfort mechanisms. (NIH/PMC — Choi, 2021)
• Circulation & Vascular Function — TRPV1-mediated vascular effects support healthy circulation. (NIH/PMC — Munjuluri, 2021)
• Gastric Protection Context — Human data show gastroprotection against irritants in healthy adults. (NIH/PMC — Mózsik, 2005)
• H. pylori Mechanisms — In vitro/experimental work indicates anti-H. pylori and anti-inflammatory activity. (NIH/PubMed — Jones, 1997; NIH/PubMed — Saha, 2022)
• Pain Pathway Support — Capsaicin desensitizes nociceptors and reduces substance P; high-concentration patch shows benefit in neuropathic pain. (NIH/PubMed — Derry, 2017; NIH/PMC — Groninger, 2012)
Additional / Promising Studies*
• Anti-Obesity Mechanisms — Reviews summarize satiety, thermogenesis, lipid oxidation pathways. (NIH/PMC — Zheng, 2017; NIH/PMC — Szallasi, 2022)
• Endurance/Exercise — Meta-analysis explores effects of capsaicin/capsiate on exercise outcomes. (Europe PMC — de Freitas, 2019)
• Brown Adipose Tissue (BAT) Angle — Reviews discuss capsinoids and BAT activation implications. (Europe PMC — Saito, 2015; Europe PMC — Osuna-Prieto, 2019)
• Gut Microbiota — Potential microbiome modulation relevant to metabolic health. (NIH/PMC — Roșca, 2020)
• Cardiometabolic Hypotheses — Vascular TRPV1, oxidative stress, and endothelial function context. (NIH/PMC — McCarty, 2015)
University / Academic Context*
• Academic groups have investigated capsaicin’s TRPV1-mediated vascular effects and metabolic thermogenesis, aligning with the benefits above. (Harvard, Tufts, OSU Linus Pauling Institute, University of Toronto)
• University-led studies contribute to evidence on appetite/satiety control and modest weight-management markers in adults.
Global Evidence & Authoritative Reviews*
• Cochrane and other authoritative reviews discuss topical capsaicin’s role in neuropathic pain management and the quality of evidence. (NIH/PubMed — Derry, 2009; NIH/PubMed — Derry, 2017)
• Public health and clinical guidance sources recognize thermogenic and digestive-support contexts for capsaicin when used appropriately. (Mayo Clinic, ODS/NIH)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
• Supports thermogenesis & energy expenditure*
• Helps appetite control & satiety*
• Supports circulation & vascular function*
• Digestive comfort support*
3rd-party tested for purity & potency
Suggested Use
Adults: Take 1 capsule daily with food, or as directed by your healthcare professional. Start low and assess tolerance. If gastric sensitivity occurs, take with a full meal.*
Product Specifications
• Serving Size — 1 capsule
• Servings Per Container — 90
• Active Ingredient(s) — Cayenne Pepper (Capsicum annuum) (fruit) 500 mg
• Free From — Non-GMO; no artificial colors or preservatives*
• Quality — Third-party tested for identity, potency & purity
3rd-Party Testing: Every batch is independently verified for identity, potency, and purity.
View our testing.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Cayenne 500 mg — supports thermogenesis, appetite control, circulation & digestive comfort; non-GMO, 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
