LifeSource Vitamins Circulation Formula — 90 Capsules
Our Circulation Formula synergistically blends Hawthorn 1.8% extract (leaves & flowers) 250 mg, Ginger Root 5% extract 100 mg, L-Arginine 50 mg, Butcher’s Broom 10% extract 25 mg, Horse Chestnut 20% extract (seeds) 25 mg, Cayenne Pepper (40M HU/G) fruit 25 mg, and Diosmin 5 mg in capsules to support healthy circulation, promote venous tone, support endothelial function, help reduce leg swelling and heaviness (CVI context), promote vascular comfort, and support overall cardiovascular wellness as part of a healthy lifestyle* — while respecting traditional use. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity and potency by LifeSource Vitamins.
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Reduces leg edema & heaviness in CVI* — Horse chestnut seed extract reduced leg volume and improved symptoms in randomized trials and Cochrane review.* NIH/PubMed — Cochrane Review, 2012
✓ Improves venous tone & microcirculation* — Butcher’s broom demonstrated efficacy vs. placebo for leg edema/venous insufficiency in double-blind RCT.* NIH/PubMed — Cesarone MR, 2002
✓ Supports healthy blood pressure* — Meta-analysis of RCTs found ginger supplementation reduced systolic and diastolic blood pressure.* NIH/PubMed — Akbari M, 2019
✓ Enhances endothelial function (NO pathway)* — L-arginine is a nitric-oxide precursor; reviews and controlled studies report improvements in endothelial function under select conditions.* NIH/PMC — Förstermann U, 2020
✓ Supports chronic venous disease with diosmin* — Clinical data (including MPFF) show decreased symptom intensity and quality-of-life improvements.* NIH/PMC — Bogachev V, 2021
✓ Promotes cardiovascular/vascular support with hawthorn* — Human trials and reviews report favorable effects on exercise capacity and vascular markers in cardiac contexts.* NIH/PubMed — Tauchert M, 2011
✓ Supports leg edema reduction with horse chestnut* — Cochrane review confirms symptom relief and edema reduction in chronic venous insufficiency.* NIH/PubMed — Cochrane Review, 2012
✓ Promotes venous insufficiency symptom relief with butcher’s broom* — Double-blind RCT showed efficacy vs. placebo for leg edema and venous tone.* NIH/PubMed — Cesarone MR, 2002
✓ Supports blood pressure reduction with ginger* — Meta-analysis of RCTs found reductions in systolic and diastolic BP.* NIH/PubMed — Akbari M, 2019
✓ Promotes endothelial function support with L-arginine* — Nitric-oxide precursor; controlled studies report improvements in select conditions.* NIH/PMC — Förstermann U, 2020
Additional / Promising Evidence
✓ Supports chronic venous disease guidance with venoactive agents* — Authoritative reviews summarize diosmin/MPFF, ruscus, and HCSE for symptom relief and edema control.* (Evidence — NIH-indexed reviews)
✓ Promotes microcirculation with butcher’s broom* — Observational/clinical investigations suggest support for capillary integrity and venous tone.* NIH/PubMed — Belcaro G, 2007
✓ Supports cayenne (capsaicin) hemodynamic context* — Emerging human data discuss microcirculatory effects in select settings.* (Evidence — NIH-indexed reviews)
✓ Promotes horse chestnut safety & usage overview* — NIH/NCCIH outlines potential to reduce CVI symptoms; safety considerations noted.* NIH/NCCIH — 2024
✓ Supports nitric-oxide–mediated vasodilation mechanisms* — L-arginine → NO pathway discussed in academic reviews.* (Evidence — NIH-indexed reviews)
✓ Promotes venoactive botanicals for CVI symptom relief* — Reviews summarize horse chestnut, ruscus, and diosmin for edema and venous tone.* (Evidence — NIH-indexed reviews)
University-Led & Academic Studies
✓ Supports mechanistic overview of venoactive agents* — Nitric-oxide–mediated vasodilation (L-arginine → NO) and venoactive botanicals (horse chestnut, ruscus, diosmin) discussed in academic reviews.* (Evidence — NIH-indexed reviews)
✓ Promotes fiber mechanisms & stool hydration research* — Academic reviews detail psyllium’s gel-forming action and water retention (related to digestive support in circulation contexts).* NIH/PMC — 2022 Review
✓ Supports IBS symptom pathways with ginger/fennel* — University-affiliated analyses discuss motility and antispasmodic effects (related to vascular/GI comfort).* NIH/PMC — 2018 Review
Global Evidence & Reviews
✓ Supports chronic venous disease guidance with venoactive agents* — Authoritative reviews summarize diosmin/MPFF, ruscus, and HCSE for symptom relief and edema control.* (Evidence — NIH-indexed reviews)
✓ Promotes horse chestnut safety & usage overview* — NIH/NCCIH outlines potential to reduce CVI symptoms; safety considerations noted.* NIH/NCCIH — 2024
✓ Supports endothelial function and NO pathway reviews* — L-arginine as precursor; controlled studies report improvements in select conditions.* NIH/PMC — Förstermann U, 2020
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
- Hawthorn 1.8% extract (leaves & flowers) 250 mg — Supports cardiovascular and vascular function.*
- Ginger Root 5% extract 100 mg — Promotes blood pressure and circulatory comfort.*
- L-Arginine 50 mg — Nitric-oxide precursor for endothelial support.*
- Butcher’s Broom 10% extract 25 mg — Supports venous tone and microcirculation.*
- Horse Chestnut 20% extract (seeds) 25 mg — Helps reduce leg edema and heaviness in CVI.*
- Cayenne Pepper (40M HU/G) fruit 25 mg — Supports circulation and warming effects.*
- Diosmin 5 mg — Promotes venous tone and chronic venous disease symptom relief.*
Brief Benefit Bullets
- Supports healthy circulation & blood flow*
- Helps reduce leg swelling & heaviness (CVI)*
- Promotes venous tone & capillary integrity*
- Endothelial/NO pathway support with L-arginine*
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3rd-party tested for purity & potency*
Suggested Use
See product label for full directions, or as directed by a healthcare professional. If pregnant, nursing, taking medications (especially anticoagulants), or have a medical condition, consult your physician.*
Product Specifications
Serving Size — 1 Capsule
Servings Per Container — 90
Form — Capsules
Key Actives (per serving) — Hawthorn extract 250 mg; Ginger extract 100 mg; L-Arginine 50 mg; Butcher’s Broom extract 25 mg; Horse Chestnut extract 25 mg; Cayenne fruit 25 mg; Diosmin 5 mg
Quality — Third-party tested for identity, potency & purity
Every LifeSource Vitamins product is 3rd-party lab tested for purity, potency, and label accuracy — because you deserve transparency and trust in every capsule.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Circulation Formula — supports healthy blood flow, venous tone & leg comfort (CVI); L-arginine + venoactive botanicals; 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
