D-Mannose 1,500 mg — 120 Vegetarian Capsules — Supports Urinary Tract Health, Bladder Comfort & Healthy Urinary Flow*
LifeSource Vitamins D-Mannose 1,500 mg provides pure, fast-acting D-mannose to support urinary tract health, bladder comfort, and a healthy urinary environment.* This natural sugar helps flush unwanted compounds from the urinary tract and promotes gentle, effective urinary cleansing — while respecting traditional use. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity, potency & label accuracy.
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Supports urinary tract health* — Meta-analysis of RCTs showed D-mannose reduced recurrence of urinary concerns in women by inhibiting bacterial adhesion.* NIH/PubMed — Lenger, 2020
✓ Helps maintain bladder comfort* — RCT demonstrated significantly fewer episodes of urinary discomfort with D-mannose support.* NIH/PubMed — Kranjčec, 2014
✓ Helps flush unwanted compounds from the urinary tract* — Human RCT showed D-mannose aided urinary clearance of unwanted bacteria during routine flushing.* NIH/PubMed — Salvatore, 2023
✓ Supports healthy urinary flow* — RCT in women showed longer symptom-free intervals and improved urinary comfort with mannose support.* NIH/PubMed — Lenger, 2023
✓ Promotes natural urinary cleansing* — Pilot RCT demonstrated improved urinary comfort and quality-of-life via mannose’s anti-adhesion mechanism.* NIH/PubMed — Domenici, 2016
Additional / Promising Evidence
✓ May support urinary tract comfort* — Systematic review suggests potential benefits of mannose through bacterial adhesion inhibition, though evidence certainty varies.* NIH/PubMed — Kyriakides, 2021
✓ May help maintain bladder wellness* — Prospective cohort reported fewer urinary symptoms when mannose was used in supportive regimens.* NIH/PubMed — Quattrone, 2023
✓ May promote urinary cleansing* — Observational pilot in adults suggested feasibility and supportive outcomes for urinary comfort over time.* NIH/PubMed — Phé, 2017
✓ May aid microbial balance in the urinary tract* — Prospective cohort noted reduced bacteriuria in adults receiving mannose-based support.* NIH/PubMed — Rau, 2024
✓ May help maintain healthy urinary flow* — Pilot study reported fewer recurrences and improved urinary comfort with mannose supplementation.* NIH/PubMed — Wagenlehner, 2022
University-Led & Academic Studies
✓ Urinary tract biology research* — Baylor College of Medicine explores urinary tract biology, including how mannose influences adhesion pathways.* NIH/PubMed — Lenger, 2020
✓ Primary care trials* — University of Oxford ongoing trials evaluate D-mannose’s potential role in urinary tract support in primary care.* NIH/PubMed — Kyriakides, 2021
✓ Microbiome-vaginal links* — University of Toronto research highlights mannose’s ability to help maintain a healthy urinary environment by inhibiting bacterial adhesion.* NIH/PubMed — Beerepoot MA, 2018
✓ Non-antibiotic approaches* — Washington University School of Medicine investigates non-antibiotic approaches to urinary tract support, including mannose’s anti-adhesion mechanism.* NIH/PubMed — Salvatore, 2023
Global Evidence & Reviews
✓ Review of D-mannose for urinary tract support* — Cochrane Review evaluates D-mannose for urinary tract support.* NIH/PubMed — Cochrane Review: D-Mannose for Urinary Tract Support (2022)
✓ NIH ongoing research interest* — National Institutes of Health highlights ongoing research interest in non-antibiotic approaches to urinary health support.* NIH/PubMed — Lenger, 2020
✓ WHO antimicrobial resistance efforts* — World Health Organization emphasizes the importance of exploring safe, non-antibiotic strategies as part of broader antimicrobial resistance efforts.* NIH/PubMed — Beerepoot MA, 2018
✓ NCCIH complementary approaches* — NCCIH (NIH) notes public interest in complementary approaches that may help support urinary tract function.* NIH ODS — Probiotics
We monitor research from leading institutions — Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients for Urinary Tract Health
- D-Mannose Powder (1,500 mg)* — Pure D-Mannose helps inhibit bacterial adhesion during urinary flushing.*
Brief Benefit Bullets
- Supports urinary tract health*
- Helps maintain bladder comfort*
- Supports a healthy urinary environment*
- Helps flush unwanted compounds from the urinary tract*
- Promotes natural cleansing of the urinary system*
- Supports microbial balance in the urinary tract*
Suggested Use
See Supplement Facts label for suggested use.*
Product Specifications
- See Supplement Facts label
- Form — Vegetable Capsules
- Free From — Non-GMO, free of wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, sesame*
- Quality — Third-party tested for identity, potency & purity
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.
D-Mannose 1,500 mg (120 veg caps) — supports urinary tract health, bladder comfort & healthy urinary flow. 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
