Glucosamine Chondroitin Plus MSM - 120 Veggie CAPSULES (Glass Bottle) 60 Servings

Glucosamine Chondroitin Plus MSM with Devil's Claw — Veggie Capsules, 120 Count — Supports Joint Health & Mobility*

LifeSource Vitamins Glucosamine Chondroitin Plus MSM with Devil's Claw delivers a balanced, research-driven formula designed to support joint health, improve comfort, and promote mobility.* Each formula is produced in FDA-registered, GMP-certified facilities and supported by NIH-indexed human clinical studies. Our approach focuses on efficacy, safety, and transparency — ensuring every ingredient meets LifeSource’s uncompromising standards for quality and science.*

• May reduce knee OA pain in moderate-to-severe cases* — In the GAIT trial, glucosamine + chondroitin helped participants with moderate-to-severe pain. (NIH/PubMed — Clegg DO, 2006)
• Comparable to celecoxib for knee OA symptoms* — Glucosamine + chondroitin was non-inferior to celecoxib in reducing pain. (NIH/PMC — Hochberg MC, 2015)
• Chondroitin: small-to-moderate benefit for pain* — Meta-analysis reported improvements in pain vs. placebo. (NIH/PubMed — Singh JA, 2015)
• Glucosamine sulfate improves knee OA symptoms* — RCT showed better outcomes vs. placebo with once-daily dosing. (NIH/PubMed — Herrero-Beaumont G, 2007)
• May slow joint-space narrowing* — 3-year study reported less narrowing with glucosamine sulfate. (NIH/PubMed — Pavelka K, 2002)
• Supports structural progression in knee OA* — Long-term glucosamine reduced joint-space loss. (NIH/PubMed — Reginster JY, 2001)
• MSM: modest pain/function improvements* — RCT showed reductions in WOMAC scores. (NIH/PubMed — Kim LS, 2006)
• MSM supports knee OA function* — Trial reported improvements in physical function. (NIH/PubMed — Debbi EM, 2011)
• Glucosamine + MSM synergy for pain* — Small RCT showed greater reductions vs. either alone. (NIH/PubMed — Usha PR, 2004)
• Devil’s Claw: musculoskeletal pain relief* — Review suggested short-term benefits. (NIH/PubMed — Gagnier JJ, 2016)
• Devil’s Claw for OA symptoms* — Trials reported pain reductions with variable quality. (NIH/PubMed — Chrubasik S, 2006)
• Mixed evidence overall* — Meta-analysis noted small effects with variability. (NIH/PubMed — Wandel S, 2010)

• Chondroitin Sulfate: may reduce cartilage loss — 2-year RCT showed less volume loss vs. celecoxib. (NIH/PMC — Wildi LM, 2016)
• Devil’s Claw: may support anti-inflammatory activity — Reviews highlight harpagoside for cytokine reduction. (NIH/PMC — Brendler T, 2021)
• Devil’s Claw: promising for pain management — Mechanistic studies show NF-κB inhibition. (NIH/PMC — Menghini L, 2022)
• MSM: may aid safety and efficacy — Narrative review notes mixed but tolerant outcomes. (NIH/PMC — Butawan M, 2017)
• Glucosamine + Chondroitin: may enhance exercise benefits — Trial explored functional gains. (NIH/PubMed — Messier SP, 2007)
• Glucosamine Sulfate: may persist long-term — RCTs suggest ongoing symptom relief. (NIH/PMC — Giordano N, 2009)
• Combination: slow-acting symptomatic relief — Classified as SYSADOA. (NIH/PMC — Bruyere O, 2023)
• MSM: may support connective tissue — Reviews highlight sulfur role. (NIH/PubMed — Debbi EM, 2011)

• Mayo Clinic: Research suggests glucosamine sulfate might relieve knee OA pain and slow degeneration, based on mixed studies needing more confirmation.
• Cleveland Clinic: MSM may aid joint pain reduction, with modest OA benefits noted in limited evidence.
• Oregon State University – Linus Pauling Institute: Devil's Claw exhibits promising anti-inflammatory effects for musculoskeletal issues, drawing from traditional and preliminary trial data.
• Harvard T.H. Chan School of Public Health: Mixed results on glucosamine/chondroitin for OA; a 2018 review indicated small symptom improvements in some patients.

• Cochrane: Meta-analysis found chondroitin provides small-to-moderate pain relief in OA, though trial quality varies. (NIH/PubMed — Singh JA, 2015)
• Cochrane: Review indicates Devil's Claw may offer moderate short-term relief for low back pain over placebo. (NIH/PubMed — Gagnier JJ, 2016)
• EFSA – European Food Safety Authority: Opinion substantiates glucosamine's role in normal joint function with regular intake.
• ABC – American Botanical Council: Monograph recognizes Devil's Claw's potential for arthritis and pain management based on historical use and studies.

Glucosamine Sulfate: Cartilage-building compound that may reduce pain and support joint function. (NIH/PubMed — Herrero-Beaumont G, 2007; NIH/PubMed — Pavelka K, 2002)

Chondroitin Sulfate: Helps maintain cartilage elasticity and may slow degradation. (NIH/PubMed — Singh JA, 2015; NIH/PMC — Wildi LM, 2016)

MSM (Methylsulfonylmethane): Sulfur source for connective tissue; may ease pain and stiffness. (NIH/PubMed — Kim LS, 2006; NIH/PMC — Butawan M, 2017)

Devil's Claw Root (5% Harpagosides): Traditional herb for inflammation and pain relief. (NIH/PubMed — Gagnier JJ, 2016; NIH/PMC — Brendler T, 2021)

• Supports joint health and cartilage maintenance*
• May reduce knee OA pain and stiffness*
• Promotes mobility and physical function*
• Aids healthy inflammatory response*
• Vegetarian-friendly veggie capsules*
• 3rd-party tested for purity and potency*

Use as directed on the Supplement Facts label, or as recommended by a healthcare professional. Do not exceed the labeled serving. Consult a physician before use if pregnant, nursing, taking medication (e.g., anticoagulants), or if you have a medical condition. Keep out of reach of children.*

• Serving Size — 2 Veggie Capsules
• Servings Per Container — 60
• Form — Capsules
• Free From — Vegetarian-friendly*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.*

LifeSource Vitamins Glucosamine Chondroitin Plus MSM with Devil's Claw supports joint health, comfort, and mobility. Vegetarian capsules, 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*