Glucosamine Chondroitin Plus MSM with Devil's Claw — 120 Veggie Capsules — Supports Joint Health & Mobility*
LifeSource Vitamins Glucosamine Chondroitin Plus MSM with Devil's Claw delivers a balanced, research-driven formula designed to support joint health*, improve comfort*, and promote mobility*. Glucosamine supports cartilage glycosaminoglycan synthesis*, chondroitin aids in retaining water for joint cushioning*, MSM provides sulfur for connective tissue support*, and Devil's Claw promotes a healthy inflammatory response*. Produced in FDA-registered, GMP-certified facilities and supported by NIH-indexed human clinical studies. Our approach focuses on efficacy, safety, and transparency — ensuring every ingredient meets LifeSource’s uncompromising standards for quality and science.*
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ May reduce knee OA pain in moderate-to-severe cases* — In the GAIT trial, glucosamine + chondroitin helped participants with moderate-to-severe pain.* NIH/PubMed — Clegg DO, 2006
✓ Comparable to celecoxib for knee OA symptoms* — Glucosamine + chondroitin was non-inferior to celecoxib in reducing pain.* NIH/PMC — Hochberg MC, 2015
✓ Chondroitin: small-to-moderate benefit for pain* — Meta-analysis reported improvements in pain vs. placebo.* NIH/PubMed — Singh JA, 2015
✓ Glucosamine sulfate improves knee OA symptoms* — RCT showed better outcomes vs. placebo with once-daily dosing.* NIH/PubMed — Herrero-Beaumont G, 2007
✓ May slow joint-space narrowing* — 3-year study reported less narrowing with glucosamine sulfate.* NIH/PubMed — Pavelka K, 2002
✓ Supports structural progression in knee OA* — Long-term glucosamine reduced joint-space loss.* NIH/PubMed — Reginster JY, 2001
✓ MSM: modest pain/function improvements* — RCT showed reductions in WOMAC scores.* NIH/PubMed — Kim LS, 2006
✓ MSM supports knee OA function* — Trial reported improvements in physical function.* NIH/PubMed — Debbi EM, 2011
✓ Glucosamine + MSM synergy for pain* — Small RCT showed greater reductions vs. either alone.* NIH/PubMed — Usha PR, 2004
✓ Devil’s Claw: musculoskeletal pain relief* — Review suggested short-term benefits.* NIH/PubMed — Gagnier JJ, 2016
Additional / Promising Evidence
✓ Chondroitin Sulfate: may reduce cartilage loss* — 2-year RCT showed less volume loss vs. celecoxib.* NIH/PMC — Wildi LM, 2016
✓ Devil’s Claw: may support anti-inflammatory activity* — Reviews highlight harpagoside for cytokine reduction.* NIH/PMC — Brendler T, 2021
✓ MSM: may support safety and efficacy* — Narrative review notes mixed but tolerant outcomes.* NIH/PMC — Butawan M, 2017
University-Led & Academic Studies
✓ Mayo Clinic: Research suggests glucosamine sulfate might relieve knee OA pain and slow degeneration, based on mixed studies needing more confirmation.*
✓ Cleveland Clinic: MSM may aid joint pain reduction, with modest OA benefits noted in limited evidence.*
✓ Oregon State University – Linus Pauling Institute: Devil's Claw exhibits promising anti-inflammatory effects for musculoskeletal issues, drawing from traditional and preliminary trial data.*
✓ Harvard T.H. Chan School of Public Health: Mixed results on glucosamine/chondroitin for OA; a 2018 review indicated small symptom improvements in some patients.*
Global Evidence & Reviews
✓ Cochrane: Meta-analysis found chondroitin provides small-to-moderate pain relief in OA, though trial quality varies.* NIH/PubMed — Singh JA, 2015
✓ Cochrane: Review indicates Devil's Claw may offer moderate short-term relief for low back pain over placebo.* NIH/PubMed — Gagnier JJ, 2016
We monitor research from leading institutions — Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
- Glucosamine Sulfate: Cartilage-building compound that may reduce pain and support joint function.*
- Chondroitin Sulfate: Helps maintain cartilage elasticity and may slow degradation.*
- MSM (Methylsulfonylmethane): Sulfur source for connective tissue; may ease pain and stiffness.*
- Devil's Claw Root (5% Harpagosides): Traditional herb for inflammation and pain relief.*
Brief Benefit Bullets
- Supports joint health and cartilage maintenance*
- May reduce knee OA pain and stiffness*
- Promotes mobility and physical function*
- Aids healthy inflammatory response*
- Vegetarian-friendly veggie capsules*
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3rd-party lab tested for purity and potency
Suggested Use
Use as directed on the Supplement Facts label, or as recommended by a healthcare professional. Do not exceed the labeled serving. Consult a physician before use if pregnant, nursing, taking medication (e.g., anticoagulants), or if you have a medical condition. Keep out of reach of children.*
Product Specifications
- Serving Size — 2 Veggie Capsules
- Servings Per Container — 60
- Form — Capsules
- Free From — Vegetarian-friendly*
- Quality — Third-party tested for identity, potency & purity
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
LifeSource Vitamins Glucosamine Chondroitin Plus MSM with Devil's Claw supports joint health, comfort, and mobility. Vegetarian capsules, 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
