Goldenseal Root — 500 mg — 100 Capsules — Convenient Immune & Respiratory Support*
LifeSource Vitamins Goldenseal Root provides Hydrastis canadensis root, naturally containing the isoquinoline alkaloids berberine and hydrastine. Goldenseal has a long history of traditional use; modern human research on its key constituents explores support for immune, respiratory, and mucosal wellness*. Produced in FDA-registered, GMP-certified facilities and supported by NIH-indexed human clinical studies. Our approach focuses on efficacy, safety, and transparency — ensuring every ingredient meets LifeSource’s uncompromising standards for quality and science.*
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Supports digestive comfort* — Systematic reviews of clinical trials report berberine-containing preparations improved diarrhea outcomes vs controls (heterogeneity noted).*
NIH/PubMed — Wang, 2020; NIH/PMC — Chu, 2020
✓ Supports IBS-D symptom relief* — Randomized clinical trial: berberine HCl reduced IBS-D symptoms and improved quality of life vs placebo.*
NIH/PubMed — Chen, 2015
✓ Characterized human exposure* — Hydrastine pharmacokinetics described after oral goldenseal in healthy adults.*
NIH/PubMed — Gurley, 2015
✓ Use with medication awareness* — Human/ex vivo data indicate goldenseal/berberine can inhibit CYP3A4/2D6/2C9; consult your physician if using medications.*
NIH/PubMed — Foster, 2003; NIH/PMC — Henderson, 2011
✓ Contemporary overview* — Narrative review summarizes chemistry, bioactivity, and evidence gaps for goldenseal.*
NIH/PubMed — Kaskoos, 2020
Additional / Promising Evidence
✓ May support respiratory/mucosal wellness* — Mechanistic data (efflux-pump inhibition and synergy) provide rationale; more human trials needed.*
NIH/PMC — Ettefagh, 2011
✓ May influence gut microbiome* — Emerging evidence links berberine to microbiota shifts; clinical relevance varies.*
NIH/PubMed — Zhang, 2019
✓ Identity and quality support* — Analytical studies define typical hydrastine/berberine ranges in authentic goldenseal.*
NIH/PMC — Applequist, 2008; NIH/PubMed — Brown, 2003
University-Led & Academic Studies
✓ Harvard: Summarizes human research on herbal constituents (incl. berberine) for digestive comfort and general wellness.*
NIH/PubMed — Anh, 2020
✓ Linus Pauling Institute (OSU): Discusses evidence and safety considerations for Botanicals affecting mucosal integrity.*
✓ Mayo Clinic: Educational reviews note traditional use; emphasize quality and medication-interaction awareness.*
Global Evidence & Reviews
✓ Cochrane: Reviews herbal/adjunct approaches across respiratory and digestive topics; evidence ranges from limited to moderate depending on endpoint.*
NIH/PubMed — Mott, 2020
✓ American Botanical Council (ABC): Monographs emphasize identity testing and authentic alkaloid profiles for quality assurance.*
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
- Goldenseal Root (Hydrastis canadensis) — 500 mg per capsule: Natural source of hydrastine and berberine; identity and quality are supported by analytical profiling of authentic goldenseal.*
Brief Benefit Bullets
- Supports immune and respiratory wellness*
- Promotes healthy mucosal tissue integrity*
- Supports digestive comfort*
- Convenient capsules for easy daily use*
-
3rd-party lab tested for purity & potency
Suggested Use
Take as directed on the product label, or as advised by a healthcare professional. If pregnant, nursing, taking medications (e.g., those metabolized by CYP3A4/2D6/2C9), or have a medical condition, consult your physician. Do not exceed recommended use. Keep out of reach of children.*
Product Specifications
- Serving Size — 1 Capsule
- Servings Per Container — 100
- Form — Vegetarian Capsules
- Free From — Non-GMO; no artificial colors or preservatives*
- Quality — Third-party tested for identity, potency & purity
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
LifeSource Vitamins Goldenseal Root — 500 mg (100 capsules) supports immune, respiratory & mucosal wellness. Non-GMO, 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*
