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Nicotinamide (NAM) — An inexpensive vitamin B3 form that feeds the NAD+ salvage pathway; at higher doses it can inhibit sirtuins (enzymes involved in DNA repair and healthy aging). (NIH/PubMed — Bitterman K, 2002); overview (NIH/PMC — Hwang E, 2017)
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Lifesource VitaminsNicotinamide Riboside (NR - Bioenergy Ribose® -RiaGev®-WS) — Newer B3 form that converts to NMN → NAD+; human trials show NR increases NAD+ levels. (NIH/PubMed — Trammell SAJ, 2016); (NIH/PubMed — Martens CR, 2018); (NIH/PubMed — Dellinger RW, 2017)
Key Takeaway: For NAD+ boosting, NR is typically more efficient than plain nicotinamide—but it’s also more expensive.
Clinically Studied Benefits
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Increases NAD+ metabolome (RiaGev®) — Randomized, triple-blind, placebo-controlled, crossover pilot in healthy middle-aged adults.
NIH/PubMed — Xue, 2022 ·
NIH/PMC — Xue, 2022
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Cellular energy/ATP substrate (D-ribose) — Open-label human pilot in CFS/FMS improved energy, sleep, and well-being vs baseline.
NIH/PubMed — Teitelbaum, 2006
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NAD coenzyme biology (niacin) — Niacin (nicotinamide/niacinamide) is a dietary precursor for NAD/NADP essential for energy metabolism.
NIH ODS — Niacin ·
OSU LPI — Niacin
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Healthy aging/skin (nicotinamide) — Phase 3 RCT: oral nicotinamide reduced new non-melanoma skin cancers in high-risk adults.
NIH/PubMed — Chen, 2015 (NEJM)
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Cutaneous immune support (nicotinamide) — Oral nicotinamide reduced UV-induced immunosuppression in volunteers.
NIH/PubMed — Yiasemides, 2009
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Antioxidant & immune support (vitamin C) — Authoritative monograph on immune and redox roles.
NIH ODS — Vitamin C
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Weight/adipokines (NAD+ precursors) — Systematic review/meta-analysis of RCTs: reduced BMI and ↑ adiponectin with NAD+ precursors.
NIH/PubMed — Baichuan, 2023
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Adipokines (niacin) — Interventional meta-analysis: niacin increased adiponectin and leptin (dose-dependent patterns).
NIH/PMC — Rad, 2024
Additional Studies Showing Promising Benefits*
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NAD biology & healthy aging* — Reviews on NAD+, sirtuins, mitochondria, and translational potential.
NIH/PubMed — Verdin, 2015 ·
NIH/PMC — Cantó, 2015 ·
NIH/PMC — Covarrubias, 2021
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University (Linus Pauling Institute), Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
• Supports NAD-dependent cellular energy pathways*
• Antioxidant support from vitamin C*
• Niacin (nicotinamide) for metabolic coenzymes NAD/NADP*
• Includes Bioenergy Ribose® (RiaGev®) for nucleotide/ATP substrate support*
• Non-GMO, gluten-free, vegan-friendly*
• Crafted in FDA-registered, GMP-certified facilities*
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3rd-party lab tested for purity & potency
Suggested Use
As a dietary supplement, take 1 capsule daily, or as directed by your healthcare practitioner. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
• Serving Size — 1 Capsule
• Servings Per Container — 30
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Form — Capsules
• Key Actives — Vitamin C; Niacin (as nicotinamide ascorbate); Bioenergy RiaGev®-WS (Bioenergy Ribose® + Nicotinamide Ascorbate)
• Free From — Non-GMO, gluten-free, vegan*
• Quality —
Third-party tested for identity, potency & purity
Perfect For
• Men and women seeking vibrant energy*
• Adults aiming for healthy aging*
• Active lifestyles focused on cellular vitality*
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
NAD+ Booster — niacin (nicotinamide ascorbate), vitamin C, and Bioenergy Ribose® to support NAD coenzymes, cellular energy, and antioxidant defenses. Clinically Studied Ingredients — NIH/PubMed!*
