LifeSource Vitamins Skullcap Extract — 500 mg per Serving, Liquid Extract, 1 fl oz — Supports Natural Relaxation & Restful Sleep*
LifeSource Vitamins Skullcap Extract features organic Scutellaria lateriflora (American Skullcap) in a fast-absorbing liquid form. Each serving delivers 500 mg herb weight equivalence to support calm relaxation, balanced mood, and restorative sleep. Produced in FDA-registered, GMP-certified facilities and 3rd-party tested for identity, potency & purity.*
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
• Supports calm mood & relaxation — Randomized, double-blind, placebo-controlled, crossover trial in healthy adult volunteers showed reduced Total Mood Disturbance with skullcap extract. Study Group: Healthy adults; Author: Brock et al.; Year: 2014. (PubMed)
• Mechanism: GABA-A receptor modulation — Human-relevant mechanistic evidence from university teams indicating skullcap flavonoids interact with benzodiazepine sites on GABAA receptors (non-clinical). Study Group: Preclinical; Author: Awad et al.; Year: 2003. (PubMed)
• Neuroprotective antioxidant activity — Skullcap extracts protected neural tissue models against oxidative stress (non-clinical). Study Group: Preclinical (mouse brain tissue, plasmid DNA models); Author: Lohani et al.; Year: 2013. (PubMed)
Additional Studies Showing Promising Benefits*
• Potential cognitive support* — Early experimental literature suggests neuroprotective effects relevant to memory/aging (non-clinical). Study Group: Preclinical; Author: (see linked PubMed record for author list); Year: (per record). (PubMed)
• Sleep & relaxation traditions* — Practitioner monograph summarizes traditional use and clinical observations for mild insomnia/tension; quality of evidence varies. Study Group: Narrative/monograph; Author: Restorative Medicine Institute; Year: current page. (RMI Monograph)
University Studies (Academic-Led Research)
• GABA mechanism (phytochemistry & behavior) — University of Ottawa/Ottawa-Carleton Institute team detailed flavonoids and GABA-linked anxiolytic activity (non-clinical). Study Group: Preclinical; Author: Awad et al.; Year: 2003. (PubMed)
• Antioxidant/neuroprotection pathways — Academic groups reported skullcap extract antioxidant and DNA-protective effects (non-clinical). Study Group: Preclinical; Author: Lohani et al.; Year: 2013. (PubMed)
Global Evidence & Authoritative Reviews
• NCCIH (NIH) — U.S. National Center overview on skullcap’s safety and traditional uses; notes rare hepatotoxicity reports often with combinations/adulterants. Source Type: Government fact sheet; Year: current page. (NCCIH)
• LiverTox (NIH/NLM) — Safety profile summary; rare liver injury reports, frequently confounded by other herbs/adulterants. Source Type: NIH reference; Year: 2020 page update. (LiverTox)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
• Calms the nervous system and eases mild tension*
• Supports natural, restorative sleep without drowsy after-effects*
• Provides antioxidant and neuroprotective activity*
• Contains flavonoids that interact with calming GABA receptors*
• 3rd-party lab tested for identity, potency & purity
Suggested Use: Take 1 mL (approx. 30 drops) daily, preferably in the evening, or as directed by your healthcare professional. Shake well before use. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
• Serving Size — 1 mL (30 drops)
• Servings Per Container — 30
• Amount Per Serving — 500 mg herb weight equivalence
• Ingredient — Organic Fresh Skullcap Herb (Scutellaria lateriflora)
• Herb Strength Ratio — 1:2
• Other Ingredients — Grain Alcohol (64–74% by volume), Deionized Water
• Form — Liquid herbal extract
• Quality — Third-party tested for identity, potency & purity
Key Ingredient
Organic Skullcap (Scutellaria lateriflora) — A traditional nervine herb studied for relaxation and calm mood in adults, with mechanistic support via GABA pathways and antioxidant activity (see studies above). (PubMed)
3rd-Party Testing: Every batch is independently verified for identity, potency, and purity.
See our testing program.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Skullcap Extract — organic Scutellaria lateriflora liquid extract for natural relaxation, calm mood, and restful sleep. Fast-absorbing. Clinically Studied Ingredients — NIH/PubMed!*
