Ultra Gut Care – L-Glutamine – NatureKnit Polyphenol Fiber Matrix — 3000 mg L-Glutamine, Powder — Supports Gut Health & Digestive Comfort*
LifeSource Vitamins Ultra Gut Care combines label-verified L-glutamine and a NatureKnit™ polyphenol fiber matrix with targeted enzymes and Saccharomyces boulardii to support a healthy gut lining, digestive comfort, and everyday GI resilience. Crafted in FDA-registered, GMP-certified facilities, this great-tasting daily powder reflects our commitment to clean, science-based nutrition guided by human studies indexed in NIH/PubMed under FDA/FTC structure-function standards.*
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Helps maintain intestinal barrier integrity* — L-glutamine supports tight-junction proteins and barrier function.
NIH/PubMed — Wang B, 2015
✓ Reduces intestinal permeability in clinical trials* — Meta-analysis shows significant decreases vs. control.
NIH/PubMed — Abbasi F, 2024
✓ Improves GI symptoms in IBS-D with leaky gut phenotype* — RCT reported symptom and permeability improvements.
NIH/PubMed — Zhou QQ, 2019
✓ Supports enterocyte fuel & mucosal recovery* — Glutamine provides epithelial energy under stress.
NIH/PMC — Rao RK, 2011
✓ Polyphenols nourish beneficial microbes & SCFA production* — Reviews indicate favorable microbiota shifts.
NIH/PubMed — Cheng H, 2023
✓ Supports digestive balance with S. boulardii* — Randomized trials show shorter duration of acute diarrhea vs. comparators.
NIH/PubMed — Mourey F, 2020
✓ Acacia (gum arabic) shows human prebiotic efficacy* — Increased bifidobacteria at ~10 g/day in adults.
NIH/PubMed — Calame W, 2008
✓ Larch arabinogalactan supports immune defense & prebiotic effects* — Human evidence indicates functional benefits.
NIH/PMC — Dion C, 2016
✓ Polyphenols modulate inflammatory pathways in the gut* — Umbrella review summarizes emerging human data.
NIH/PubMed — Mao T, 2024
✓ Overall synergy: glutamine + prebiotic fibers* — Complementary support for barrier function and SCFAs.
NIH/PubMed — Achamrah N, 2017
Additional / Promising Evidence
✓ Glutamine may further improve permeability in short-term protocols* — meta-analysis signal.
NIH/PMC — Abbasi F, 2024
✓ Acacia gum is well-tolerated and bifidogenic* — in healthy humans.
NIH/PubMed — Calame W, 2008
✓ Larch arabinogalactan demonstrates prebiotic/immune actions* — (human evidence).
NIH/PMC — Harris S, 2019
✓ S. boulardii benefits replicated across RCTs* — for acute diarrheal support.
NIH/PubMed — Altcheh J, 2022
✓ Polyphenols + fiber may drive butyrate generation* — via microbiota fermentation.
NIH/PubMed — Maiuolo J, 2024
✓ Glutamine supports epithelial energy needs* — under stress conditions.
NIH/PMC — Rao RK, 2011
University-Led & Academic Studies
✓ Harvard — Research programs examine diet–microbiome interactions and SCFA-mediated gut health.
NIH/PubMed — General academic resource
✓ Johns Hopkins — Investigations into epithelial barrier biology and mucosal immunity.
NIH/PubMed — General academic resource
✓ Oregon State University – Linus Pauling Institute — Work on polyphenols, antioxidants, and GI function.
NIH/PubMed — General academic resource
Global Evidence & Reviews
✓ World Health Organization — Dietary fiber is widely recognized for supporting digestive health and overall wellness.
NIH/ODS — General fiber fact sheet
✓ American Gastroenterological Association — Evidence reviews address probiotics and dietary strategies for GI comfort.
NIH/PubMed — General review resource
✓ NIH — PubMed/PMC host clinical evidence on glutamine, polyphenols, and S. boulardii related to digestive support.
NIH/PubMed — General resource
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
-
L-Glutamine — primary fuel for enterocytes; supports barrier integrity and mucosal recovery.*
-
NatureKnit™ Polyphenol Fiber Matrix — polyphenol-rich fibers that help cultivate beneficial microbes and SCFAs.*
-
Saccharomyces boulardii — clinically studied probiotic yeast for digestive balance.*
-
Gluten Enzyme Formula — targeted enzymes to support macronutrient breakdown.*
Brief Benefit Bullets
- Supports a healthy gut lining & balanced permeability*
- Promotes digestive comfort & everyday GI resilience*
- Polyphenol fiber matrix nourishes beneficial gut microbes*
- Includes S. boulardii for digestive balance*
- Plant-based enzymes support macronutrient breakdown*
- Non-GMO, gluten-free; mixes easily into water or smoothies*
- Vegan-friendly formula; gentle for everyday use*
- Great tasting; convenient once-daily scoop*
Suggested Use
See product label for full instructions, or as directed by your healthcare professional. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
-
Serving Size — 1 Scoop (3.86 g)
-
Form — Powder
-
Key actives per serving — L-Glutamine 3000 mg; NatureKnit™ Polyphenol Fiber Matrix 2000 mg; Gluten Enzyme Formula 850 mg; Saccharomyces boulardii 5 Billion CFU†
-
Free From — Non-GMO, gluten-free; no artificial colors, preservatives or synthetic chemicals*
-
Quality — Manufactured in FDA-registered, GMP-certified facilities
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ultra Gut Care — 3000 mg L-Glutamine powder. Supports gut lining, digestive comfort & microbiome balance; non-GMO. Clinically Studied Ingredients — NIH/PubMed!*
