Vitamin B-12 Complex Sublingual --- 1,000 mcg, Liquid, 2 fl. oz. --- Supports Energy & Nervous System Health*
Lifesource Vitamins Vitamin B-12 Complex Sublingual combines clinically studied methylcobalamin with B-vitamins (B-1, B-2, B-3, B-5, B-6, folate) and vitamin C to support energy metabolism, nervous-system health, red blood cell formation, and cognitive well-being—especially in individuals with low or borderline B-12 status. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for identity, potency & purity.*
Research Promise: At Lifesource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
- Corrects B-12 deficiency (hematologic & neurologic) — High-dose oral B-12 (1,000–2,000 mcg/day) was as effective as intramuscular injections in RCTs for deficiency, normalizing blood markers and supporting neurologic outcomes. (Vidal-Alaball 2005, PubMed; Cochrane 2018, PMC)
- Nervous-system support in neuropathy — Oral methylcobalamin 1 mg/day for 12 months improved neurophysiology, sudomotor function, pain scores, and quality of life in diabetic neuropathy vs placebo (DB-RCT). (Didangelos 2021, PMC)
- Symptom improvement in diabetic neuropathy — Double-blind trial reported improvements in somatic/autonomic symptoms with methylcobalamin vs placebo. (Yaqub 1992, PubMed)
- Adjunctive therapy benefit — In a randomized, double-blind study, methylcobalamin + alpha-lipoic acid outperformed methylcobalamin alone for neuropathic symptom reduction. (Cross 2023, PMC)
- Perceived stress & mood (selected populations) — RCTs and meta-analyses show B-complex formulations can reduce perceived stress and improve mental well-being in stressed adults. (Stough 2014, PMC; Kennedy 2010, PubMed; Young 2019, PMC)
- Cognitive aging (mixed) — Meta-analysis suggests B-vitamin supplementation may slow cognitive decline in certain groups (longer duration/early intervention), though findings are not universal. (Wang 2022, PubMed)
Promising/Traditional (with human data & limitations)*
- Homocysteine & cardiovascular outcomes* — B-vitamins lower homocysteine, but large RCTs did not show reductions in major cardiovascular events. (HOPE-2, NEJM 2006)
- Mood disorders* — Some RCTs of B-complex show benefits for stress/overall mood; effects on clinical depression/anxiety are small or inconsistent. (Young 2019, PMC)
University & Global Studies (Human — PubMed/PMC-Linked)
- Oral vs IM B-12 in deficiency (Cochrane RCTs) — High-dose oral therapy comparable to injections for biochemical and hematologic response. (Cochrane 2018, PMC)
- Methylcobalamin in diabetic neuropathy — Placebo-controlled human trials and adjunctive-therapy RCTs report symptom and function improvements. (Didangelos 2021, PMC; Cross 2023, PMC)
- B-complex & stress — Randomized trials/meta-analysis indicate reduced perceived stress in healthy/stressed adults. (Stough 2014, PMC; Young 2019, PMC)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
- Supports energy metabolism — especially when correcting low or borderline B-12*
- Helps maintain healthy nerves & myelin*
- Promotes red blood cell formation; helps resolve megaloblastic anemia due to B-12 deficiency*
- Supports cognitive well-being in select populations*
- May reduce perceived stress in stressed adults (select RCTs)*
- 3rd-party lab tested for purity & potency
Suggested Use
Place 1 dropper (1 mL) under the tongue daily; hold for 30 seconds before swallowing, or as directed by your healthcare professional. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
- Serving Size — 1 Dropper (1 mL)
- Servings Per Container — 59
- Form — Liquid (Sublingual)
- Free From — Non-GMO, gluten-free, vegan*
- Quality — Third-party tested for identity, potency & purity
Perfect For:
- Individuals seeking support for energy metabolism & mental clarity*
- Vegetarians/vegans and older adults at risk for low B-12*
- Those managing stress or fatigue related to suboptimal B-vitamin status*
Key Ingredients
Vitamin B-12 (Methylcobalamin) — Essential for neurologic function and red blood cell production; high-dose oral therapy is effective for deficiency (human RCTs). (Vidal-Alaball 2005; Cochrane 2018)
Vitamin B-6 (Pyridoxine) & Folate (B-9) — Support neurotransmitter synthesis and homocysteine metabolism; mood/stress benefits shown in select trials/meta-analysis. (Young 2019, PMC)
Vitamin C — Antioxidant support and overall wellness.*
Lifesource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Vitamin B-12 Complex Sublingual — supports energy metabolism, nerves & red blood cells. Human studies (PubMed/PMC) + 3rd-party tested!*
