Vitamin D-3 250 mcg (10,000 IU) – 90 Softgels – Bone & Immune Support*
High-potency Vitamin D3 (cholecalciferol) to support strong bones, immune health, and overall vitality. Delivers 10,000 IU per softgel to correct low vitamin D status and promote wellness. Produced in FDA-registered, GMP-certified facilities and 3rd-party lab tested for purity, potency, and label accuracy. (This is a higher-dose product—consult your healthcare professional.)
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from leading health organizations and insights from top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits
✓ Supports bone health & calcium absorption — Vitamin D3 increases intestinal calcium absorption and helps maintain bone mineral density.
NIH/PubMed — 2020
✓ Supports immune function (respiratory) — Meta-analysis of randomized trials shows vitamin D reduces acute respiratory infection risk, especially in those deficient at baseline.
NIH/PubMed — Martineau, 2017
✓ Supports muscle function & falls (older adults) — Trials and reviews associate vitamin D repletion with improved muscle function and reduced fall risk.
NIH/PubMed — Gillespie, 2011
✓ Cardiometabolic markers (adjunct) — Evidence suggests vitamin D may influence endothelial function and inflammation; findings are mixed across trials.
NIH/PubMed — 2021
✓ Mood & mental health (adjunct) — Observational and interventional data link low vitamin D with depressed mood; supplementation shows signals for benefit in some groups.
NIH/PubMed — 2020
✓ Cancer outcomes (adjunct) — Large RCTs and pooled analyses report reduced cancer mortality (not incidence) with vitamin D supplementation.
NIH/PubMed — 2018
✓ Glucose/insulin sensitivity (select groups) — Some trials show improved insulin sensitivity in deficient individuals.
NIH/PubMed — 2019
✓ Prevents rickets/osteomalacia — Essential for normal bone mineralization across the lifespan.
NIH/PubMed — 2021
Additional / Promising Evidence
✓ Autoimmune modulation — Epidemiology and early interventional work suggest risk reduction in certain autoimmune conditions.
NIH/PubMed — 2019
✓ Blood pressure (adjunct) — Mixed RCT data; potential effects via renin–angiotensin modulation.
NIH/PubMed — 2021
✓ Cardiovascular events (adjunct) — Heterogeneous findings across trials; benefit may depend on baseline status.
NIH/PubMed — 2021
✓ Colorectal polyp risk — Some data suggest lower risk with adequate vitamin D status.
NIH/PubMed — 2014
✓ Cognition/brain aging (adjunct) — Associations with slower decline in some cohorts; intervention data are evolving.
NIH/PubMed — 2022
✓ Fatigue/energy (adjunct) — Repletion may improve fatigue in deficient adults.
NIH/PubMed — 2022
✓ Respiratory support — Signals for reduced infection severity in deficient groups.
NIH/PubMed — 2022
✓ Mood stability (adjunct) — Meta-analytic signals for reduced depressive symptoms in some populations.
NIH/PubMed — 2021
University-Led & Academic Studies
✓ Supports bone strength & mineralization — D3 (800 IU/day) + calcium reduced hip and non-vertebral fractures in older women in a landmark randomized trial.
NIH/PubMed — Chapuy, 1992
✓ Enhances calcium absorption — Controlled human studies show D3 repletes 25(OH)D and improves fractional calcium absorption, a key mechanism for bone health.
NIH/PubMed — Heaney, 2003
✓ Helps prevent falls in older adults — Meta-analysis of RCTs found vitamin D (≈700–1,000 IU/day) reduced fall risk versus control.
NIH/PubMed — Bischoff-Ferrari, 2004
Global Evidence & Reviews
✓ NIH ODS Vitamin D Fact Sheet (Health Pros) — Evidence, dosing, and safety overview for clinicians.
NIH/ODS — Vitamin D
✓ Harvard T.H. Chan School — Educational review on vitamin D and health (bones, immunity, chronic disease context).
Harvard — Vitamin D
✓ Johns Hopkins Medicine — Patient-level guidance on vitamin D and immunity.
Johns Hopkins — Vitamin D & Immunity
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
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Vitamin D3 (Cholecalciferol) — Supports calcium absorption, bone & muscle function, and immune health. (NIH/ODS — Vitamin D)
Brief Benefit Bullets
- Supports bone health & calcium absorption*
- Helps immune defenses (respiratory support in deficient groups)*
- Aids muscle function; supports healthy fall risk in older adults*
- Adjunct support for cardiometabolic and mood markers*
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3rd-party lab tested for purity, potency & accuracy
Suggested Use
Take as directed on the label, with food to enhance absorption, or as directed by your healthcare professional. Because 10,000 IU is a higher dose, use only under medical supervision and monitor serum 25(OH)D as appropriate.*
Product Specifications
• Serving Size — 1 softgel
• Servings Per Container — 90
• Active — Vitamin D3 (cholecalciferol) — 250 mcg (10,000 IU) per softgel
• Form — Softgels
• Free From — Non-GMO, gluten-free, no artificial colors*
• Quality — Third-party tested for identity, potency & purity
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Vitamin D3 10,000 IU — high-potency softgels for bone, immune & muscle support; human-study referenced (NIH/PubMed). Clinically Studied Ingredients — NIH/PubMed!*
