Vitamin D-3 250 mcg (10,000 IU) – 90 Softgels – Bone & Immune Support*
High-potency Vitamin D3 (cholecalciferol) to support strong bones, immune health, and overall vitality.* Delivers 10,000 IU per softgel to correct low vitamin D status and promote wellness.* Produced in FDA-registered, GMP-certified facilities and
3rd-party lab tested for purity, potency, and label accuracy.*
(This is a higher-dose product—consult your healthcare professional.)
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
• Supports bone health & calcium absorption — Vitamin D3 increases intestinal calcium absorption and helps maintain bone mineral density. (PubMed 2020; NIH ODS)
• Immune function (respiratory) — Meta-analysis of randomized trials shows vitamin D reduces acute respiratory infection risk, especially in those deficient at baseline. (BMJ 2017)
• Muscle function & falls (older adults) — Trials and reviews associate vitamin D repletion with improved muscle function and reduced fall risk. (Cochrane Review; Harvard Health)
• Cardiometabolic markers (adjunct) — Evidence suggests vitamin D may influence endothelial function and inflammation; findings are mixed across trials. (PubMed 2021; NCCIH)
• Mood & mental health (adjunct) — Observational and interventional data link low vitamin D with depressed mood; supplementation shows signals for benefit in some groups. (PubMed 2020; OSU Linus Pauling Institute)
• Cancer outcomes (adjunct) — Large RCTs and pooled analyses report reduced cancer mortality (not incidence) with vitamin D supplementation. (NEJM 2018)
• Glucose/insulin sensitivity (select groups) — Some trials show improved insulin sensitivity in deficient individuals. (NEJM 2019)
• Prevents rickets/osteomalacia — Essential for normal bone mineralization across the lifespan. (PubMed 2021)
Additional Studies Showing Promising Benefits*
• Autoimmune modulation* — Epidemiology and early interventional work suggest risk reduction in certain autoimmune conditions. (Frontiers Immunol. 2019)
• Blood pressure (adjunct)* — Mixed RCT data; potential effects via renin–angiotensin modulation. (PubMed 2021)
• Cardiovascular events (adjunct)* — Heterogeneous findings across trials; benefit may depend on baseline status. (PubMed 2021)
• Colorectal polyp risk* — Some data suggest lower risk with adequate vitamin D status. (AJCN 2014)
• Cognition/brain aging (adjunct)* — Associations with slower decline in some cohorts; intervention data are evolving. (PubMed 2022)
• Fatigue/energy (adjunct)* — Repletion may improve fatigue in deficient adults. (PubMed 2022)
• Respiratory support* — Signals for reduced infection severity in deficient groups. (PubMed 2022)
• Mood stability (adjunct)* — Meta-analytic signals for reduced depressive symptoms in some populations. (PubMed 2021)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
• Supports bone health & calcium absorption*
• Helps immune defenses (respiratory support in deficient groups)*
• Aids muscle function; supports healthy fall risk in older adults*
• Adjunct support for cardiometabolic and mood markers*
• 3rd-party lab tested for purity, potency & accuracy
Suggested Use: Take as directed on the label, with food to enhance absorption, or as directed by your healthcare professional. Because 10,000 IU is a higher dose, use only under medical supervision and monitor serum 25(OH)D as appropriate.*
Product Specifications
• Serving Size — 1 softgel
• Servings Per Container — 90
• Active — Vitamin D3 (cholecalciferol) — 250 mcg (10,000 IU) per softgel
• Form — Softgels
• Free From — Non-GMO, gluten-free, no artificial colors*
• Quality — Third-party tested for identity, potency & purity
Perfect For
• Adults with limited sun exposure*
• Individuals needing high-potency repletion under clinician guidance*
• Those seeking bone, immune, and mood support*
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Vitamin D3 10,000 IU — high-potency softgels for bone, immune & muscle support; human-study referenced (NIH/PubMed). Clinically Studied Ingredients — NIH/PubMed!*
